Silk Road forums

Discussion => Drug safety => Topic started by: cabinman01 on May 11, 2013, 01:03 am

Title: Adderall - IR vs. XR
Post by: cabinman01 on May 11, 2013, 01:03 am
Okay, so I have taken Adderall 20mg IR plenty of times and it usually does the trick.  Sometimes I even break them in half and use just 10mg and it works alright.  My tolerance is fairly low I would say, and I also don't use them all that often(only for big exams and finals).  My question is, in your experience would you say that Adderall IR or XR works better in general?

 I have never taken the XR's, and which mg of XR would work the best for a whole day for someone with low tolerance?

Title: Re: Adderall - IR vs. XR
Post by: SelfSovereignty on May 11, 2013, 01:17 am
It's a little less straight forward than that.  Adderall XR is an extended release formulation -- basically that means that it dissolves more slowly in your intestines than the instant release tablets.

So 20mg of instant release is instantly released and pretty much totally absorbed within an hour of ingestion.  Give or take -- I always seemed to reach peak levels almost exactly 43 minutes after taking it, but your mileage may vary and I'm no biologist and all that disclaimer stuff :)

20mg of XR though, would be released slowly over a period of about 2 hours maybe (give or take).  I've never paid attention the extended release ones though, so I can't compare my own experience with them.  In the end though, it's basically like taking a quarter of an instant release every 20-30 minutes.  That's the difference.  Which is better is up to you and the situation you're in :)
Title: Re: Adderall - IR vs. XR
Post by: cabinman01 on May 11, 2013, 01:26 am
Thanks for the info.  I am basically just trying to see which is a better bang for a buck, the prices are ridiculous on SR. On the other hand, has anyone tried Focalin? I know it has similar properties to Adderall, but I've never tried it.
Title: Re: Adderall - IR vs. XR
Post by: SelfSovereignty on May 11, 2013, 01:51 am
You could try some speed and see if that does the trick for you.  It works for many, but for many it just doesn't do the job.  Either way though, it's awfully cheap amphetamine sulfate -- you can get a gram of speed for about 20-30 bucks (which is anywhere from 40-80% pure amphetamine sulfate: so at least 400mg of it, or 20 adderall 20mg tablets).

Fair warning, it's often mixed with caffeine and usually only available from Europe (not really a US thing -- it's all meth in the US).  CapeCrusader and BoyMaster are generally considered the two best vendors if you want to check them out.
Title: Re: Adderall - IR vs. XR
Post by: b0lixtrader on May 11, 2013, 03:32 am
XR's give me way more side effects than IRs.

I don't know why because it's not because I take so much more XR's dosage wise.  That said XRs also seem way more potent too.  I'm talking about both the actual original brand kind too.

XR's if I take 40+ in a day I will have the worse high blood pressure side effects where I almost pass out when I'm walking and my vision goes blurry and then total white to red.  Not to add that I feel like total shit when I'm crashing.

Definitely feels better and for longer but the sides of XR's aren't worth it if I take higher doses.
Title: Re: Adderall - IR vs. XR
Post by: cabinman01 on May 11, 2013, 04:55 am
You could try some speed and see if that does the trick for you.  It works for many, but for many it just doesn't do the job.  Either way though, it's awfully cheap amphetamine sulfate -- you can get a gram of speed for about 20-30 bucks (which is anywhere from 40-80% pure amphetamine sulfate: so at least 400mg of it, or 20 adderall 20mg tablets).

Fair warning, it's often mixed with caffeine and usually only available from Europe (not really a US thing -- it's all meth in the US).  CapeCrusader and BoyMaster are generally considered the two best vendors if you want to check them out.

I will definately look into that.  I never really thought of considering that, but it is essentially the same I suppose and considerably cheaper.  Thanks SS

XR's give me way more side effects than IRs.

I don't know why because it's not because I take so much more XR's dosage wise.  That said XRs also seem way more potent too.  I'm talking about both the actual original brand kind too.

XR's if I take 40+ in a day I will have the worse high blood pressure side effects where I almost pass out when I'm walking and my vision goes blurry and then total white to red.  Not to add that I feel like total shit when I'm crashing.

Definitely feels better and for longer but the sides of XR's aren't worth it if I take higher doses.

40+ would really be way too much for me, hah.  It sounds like it might be a little much for you as well!  :P
Thanks for the info
Title: Re: Adderall - IR vs. XR
Post by: b0lixtrader on May 11, 2013, 05:25 am
My point was IR at the same dosage and no side effects.

First time ever taking adderall XR's was 60mg.  Was still a new recreational user with a virgin brain so I stayed up for 2 days.  However, the euphoria was bliss and was comparable to a 100mg MDMA roll.  Good times till the sides kicked in.

15-20mg XR's I can handle well.
Title: Re: Adderall - IR vs. XR
Post by: SelfSovereignty on May 11, 2013, 07:21 am
That's really weird, B0lix.  Are you absolutely 100% certain that what you got was actual Adderall?  Bear in mind that if you got XR gel caps, someone could easily have replaced the contents with something other than adderall -- I mean was it straight from the pharmacy or what?
Title: Re: Adderall - IR vs. XR
Post by: jackofspades on May 11, 2013, 09:39 am
Thanks for the info.  I am basically just trying to see which is a better bang for a buck, the prices are ridiculous on SR. On the other hand, has anyone tried Focalin? I know it has similar properties to Adderall, but I've never tried it.

My gf just tried focalin she said it was more like molly than adderall, 10mg lasted only about 3 hours and took 20 min to kick in she said, she took it with a friend who took 20mg of it and fainted, then slept-off the the 'come down' which they said was very unpleasant (similar to a MDMA come down).
Title: Re: Adderall - IR vs. XR
Post by: b0lixtrader on May 11, 2013, 09:41 am
Lol yea straight from the pharmacy.

I'm assuming it was just overdosing.  Maybe the half life of the XR's has something to do with it. 
Title: Re: Adderall - IR vs. XR
Post by: cabinman01 on May 13, 2013, 01:46 am
Thanks for the info.  I am basically just trying to see which is a better bang for a buck, the prices are ridiculous on SR. On the other hand, has anyone tried Focalin? I know it has similar properties to Adderall, but I've never tried it.

My gf just tried focalin she said it was more like molly than adderall, 10mg lasted only about 3 hours and took 20 min to kick in she said, she took it with a friend who took 20mg of it and fainted, then slept-off the the 'come down' which they said was very unpleasant (similar to a MDMA come down).

Wow, that does not sound very pleasant at all.  I looked and there is only one vendor on the road that sells Focalin anyway, same price as Addys.  Glad for the info, I was gonna purchase some.
Title: Re: Adderall - IR vs. XR
Post by: cabinman01 on May 13, 2013, 01:55 am
My point was IR at the same dosage and no side effects.

First time ever taking adderall XR's was 60mg.  Was still a new recreational user with a virgin brain so I stayed up for 2 days.  However, the euphoria was bliss and was comparable to a 100mg MDMA roll.  Good times till the sides kicked in.

15-20mg XR's I can handle well.

Ahh, I gotcha.  The Adderall XR's at about 20 to 30 mg would probably suite me then.
And I can attribute to the euphoria of Adderall, for my first time at least.  The first time I took it, I took a 20 mg IR, and it was godly.  haha. 

-On a side note, I am studying for my biggest final exam, and I have no Addys currently... :(
This will be interesting...
Title: Re: Adderall - IR vs. XR
Post by: NewStem on May 13, 2013, 02:49 am
It's a little less straight forward than that.  Adderall XR is an extended release formulation -- basically that means that it dissolves more slowly in your intestines than the instant release tablets.

So 20mg of instant release is instantly released and pretty much totally absorbed within an hour of ingestion.  Give or take -- I always seemed to reach peak levels almost exactly 43 minutes after taking it, but your mileage may vary and I'm no biologist and all that disclaimer stuff :)

20mg of XR though, would be released slowly over a period of about 2 hours maybe (give or take).  I've never paid attention the extended release ones though, so I can't compare my own experience with them.  In the end though, it's basically like taking a quarter of an instant release every 20-30 minutes.  That's the difference.  Which is better is up to you and the situation you're in :)

I just want to step in and correct your description of the mechanism of Adderall XR:

Half the contents in an Adderall XR cap are the same form of amphetamine present in the IR version. The other half is a form of amphetamine metabolized lower in the digestive system, its effects beginning maybe 4 or 5 hours after the initial release. The drug does NOT release slowly over time, but rather releases in 2 waves many hours apart.
Title: Re: Adderall - IR vs. XR
Post by: SelfSovereignty on May 13, 2013, 07:04 am
It's a little less straight forward than that.  Adderall XR is an extended release formulation -- basically that means that it dissolves more slowly in your intestines than the instant release tablets.

So 20mg of instant release is instantly released and pretty much totally absorbed within an hour of ingestion.  Give or take -- I always seemed to reach peak levels almost exactly 43 minutes after taking it, but your mileage may vary and I'm no biologist and all that disclaimer stuff :)

20mg of XR though, would be released slowly over a period of about 2 hours maybe (give or take).  I've never paid attention the extended release ones though, so I can't compare my own experience with them.  In the end though, it's basically like taking a quarter of an instant release every 20-30 minutes.  That's the difference.  Which is better is up to you and the situation you're in :)

I just want to step in and correct your description of the mechanism of Adderall XR:

Half the contents in an Adderall XR cap are the same form of amphetamine present in the IR version. The other half is a form of amphetamine metabolized lower in the digestive system, its effects beginning maybe 4 or 5 hours after the initial release. The drug does NOT release slowly over time, but rather releases in 2 waves many hours apart.

Indeed, you're right.  Half of the medication is contained in beads that dissolve and release the four amphetamine salts 4 hours after initial ingestion (give or take).  Since the four salts in adderall all have slightly different digestive profiles anyway, it's a little less straight forward than two waves, but again: you're absolutely right about the XR mechanism releasing the four salts in two waves.  Thank you for the correction :)