Silk Road forums

Market => Product offers => Topic started by: Tryptamine on August 02, 2011, 08:58 pm

Title: ⋋ Better Living Through Neurochemistry 乂 Protect, Repair & Enhance Your Brain ⋌
Post by: Tryptamine on August 02, 2011, 08:58 pm
http://silkroadvb5piz3r.onion/silkroad/user/44143e1f2f

I am a biologist who designs safe, brain-targeting supplements using vitamins, herbal extracts, metabolites, and smart drugs.
Unlike all other producers of nutritional supplements, I use only the highest quality ingredients, and strive to "first do no harm".

My products:

MindFood
24-Bottle: http://silkroadvb5piz3r.onion/silkroad/item/4eb0d69886

ChillPill
24-Bottle: http://silkroadvb5piz3r.onion/silkroad/item/4dc5679867
Title: Re: Nootropic supplements
Post by: nomad bloodbath on August 11, 2011, 08:11 pm
A "smart pill" would be awesome.....everyone here needs a bottle of them.

:S
nomad bloodbath
Title: Re: Nootropic supplements
Post by: jesusjoints on August 14, 2011, 09:36 am
if you could get the nootropics joe rogan is talking about here i'd be interested XD
http://www.youtube.com/watch?v=hz4EFKkkMkM
Title: Re: Nootropic supplements
Post by: jesusjoints on August 14, 2011, 10:02 pm
The ChillPill will make you dream, if that's what you're looking for

nah not when they are talking about dreaming.. they briefly talk about joe rogans collection of nootropics but they dont say whats in them! :(
Title: Re: Nootropic supplements
Post by: Tryptamine on August 15, 2011, 01:09 am
My MindFood capsules are nootropic, although they're meant more for preventing/alleviating brain damage and discomfort (hangovers, MDMA 'depletion', post-LSD feeling, tedious coursework, etc) and promoting optimal brain function than for expanding brain capacity/abilities. If you want an explicitly mind-expanding 'smart pill' I'll probably have it ready within the next couple of weeks.
Title: Re: Nootropic supplements
Post by: Tryptamine on September 15, 2011, 09:59 pm
I now have new and improved MindFood capsules in stock; they now contain sulbutiamine, a modified dimer of thiamine (B1) that goes straight to the brain, and rhodiola rosea, an adaptogenic and endurance-boosting herb. I plan to have the first version of a 'smart pill' out probably next week, if not earlier.
Title: Re: Nootropic supplements
Post by: Tryptamine on September 23, 2011, 11:53 pm
New ChillPills in stock, now with more picamilon
Title: Re: Nootropic supplements
Post by: Tryptamine on December 09, 2011, 06:22 pm
After a 1+ month hiatus, I will have my supplements back up for sale within the next week. I've improved the formulas and am now using the most bioavailable vitamers available, including Pyridoxal-5-Phosphate (the expensive, bioidentical form of B6) and Na-R-ALA (sodium stabilized, enantiopure alpha lipoic acid).
Title: Re: Nootropic supplements
Post by: crib on December 09, 2011, 09:37 pm
I'll be watching. Very interested in these.
Title: Re: Nootropic supplements
Post by: max12345 on December 10, 2011, 03:15 am
keep me posted too thank you.
Title: Re: Nootropic supplements
Post by: reginaldquincy on December 10, 2011, 08:33 am
what's in your "smart pill" plan?
if { Piracetam? Oxiracetiam? Ani? Pram?
   Why sell on SR
else { What is the active ingredient?

Will it be instant or will redosing be needed to achieve a noticeable effect? 
Title: Re: Nootropic supplements
Post by: Blackface on December 10, 2011, 01:21 pm
How does it compare to Alpha Brain, Shroomtech other nootrpoics from Onnit?
Title: Re: Nootropic supplements
Post by: fatalz on December 11, 2011, 11:14 pm
I never saw your seller thread. What are the prices for the 3 of your pills? What quantities do you sell them in? and how long will they need to be taken for an effect to be noticed?
Title: Re: Nootropic supplements
Post by: HeyHeyItsSaturday on December 11, 2011, 11:29 pm
Hello!

Is taking 5 HTP for MDMA recovery worthwhile and if so is it better to take before or after rolling?

Does Magnesium Oxide really preventing jaw clenching?

Whats a good antioxidant to take after a big weekend?
Title: Re: Nootropic supplements
Post by: slothmc on December 12, 2011, 03:57 am
Hello!

Is taking 5 HTP for MDMA recovery worthwhile and if so is it better to take before or after rolling?

Does Magnesium Oxide really preventing jaw clenching?

Whats a good antioxidant to take after a big weekend?

5-htp helps with recovery after you roll, its pointless preloading on it as it replaces part of missing serotonin. I have used a few times after rolling and it defiantly helped me sleep, I slept deeper and longer then when I didn't post load with it. And I also felt a difference the day after.

Magnesium preloading may alleviate some jaw tension as it helps relief muscular cramps but i've never tried it (always have gum on hand) :P
Title: Re: Nootropic supplements
Post by: HeyHeyItsSaturday on December 12, 2011, 04:45 am
Thanks for the reply :)

I don't get depressed or have any problems in the weeks following mdma use but if there is something that could replenish what i'm burning off and get back to normal i would give it a go but i usually take around 1mg of xanax and that puts me to sleep so 5htp wouldn't do much for me i guess but i will get some magnesium oxide and see how it goes this weekend as i don't like gum or chupa chups (which are popular with my friends) when i'm high...
Title: Re: Nootropic supplements
Post by: Tryptamine on December 13, 2011, 10:17 pm
what's in your "smart pill" plan?
if { Piracetam? Oxiracetiam? Ani? Pram?
   Why sell on SR
else { What is the active ingredient?

Will it be instant or will redosing be needed to achieve a noticeable effect?

Each of the 13 ingredients are active, and while the individual dosages of each may be low, many of the components synergize with or otherwise potentiate others.
But to answer your question, as far as racetams it includes piracetam and aniracetam. I'm selling these products here because everyone here already takes drugs, because bitcoins are sometimes more useful to me than USD, and because it's a good place to get feedback and modify my products.
There are acute effects felt after a single use, although if you continue to take them there are cumulative benefits.

How does it compare to Alpha Brain, Shroomtech other nootrpoics from Onnit?

Onnit's products appear to be trying to induce a specific mental state in you and include chemicals that they think will do so. For example, 'alphabrain' contains huperazine, pterostilbene, and vinpocetine, which are potent neurotropic substances, as well as a few vitamins and neurotransmitter precursors. My products contain some of the same (or analogous) components as do onnit's, but I have avoided using drugs that I feel are too potent or have too small a dosage range, to minimize potential adverse reactions.
That's not to say their products are more effective than mine; my products contain many ingredients that theirs do not, and I use the highest-quality, most bioavailable forms of the substances I include, while they don't always do so. Here is a comparison between ThinkDeep and onnit's AlphaBrain:

ThinkDeep
1.
20mg Pyridoxal-5-Phosphate (B6)
2.
100mg Eluthero Sibiricus extract (0.8% elutherosides)
100mg Bacopa Monneri extract (20% bacosides)
100mg Rhodiola Rosea extract (3% rosavins)
100mg Ginkgo Biloba extract (24% Ginkgosides)
60mg Pine Bark Extract (98% Oligomeric Proanthocyanidins)
60mg Grape Seed Extract (99% OPCs)
3.
100mg N-Acetyl-Tyrosine (NALT)
20mg 5-HydroxyTryptophan (5-HTP)
30mg Picamilon (B3 & GABA)
5.
100mg Acetyl-L-Carnitine (ALCAR)
50mg Na-R-Alpha Lipoic Acid (NA-RALA)
60mg Sulbutiamine (B1)
6.
400mg Piracetam
150mg Anracetam


AlphaBrain:
1.
15mg Pyridoxine (B6)
2.
300mg 10:1 Oat Straw extract
500mg Bacopa Monneri extract
350mg Cat's Claw extract (AC-11)
3.
200mg Mucuna Pruriens (50% L-DOPA)
200mg GABA
5.
100mg GPC choline
6.
250ug Huperazine A
250ug Pterostilbene
5mg Vinpocetine

1. Vitamin B6
ThinkDeep contains 20mg Pyridoxal-5-Phosphate, the active coenzyme form of vitamin B6, which is required for (among other things) the synthesis of monoamine neurotrannsmitters from their respective amino acids.

AlphaBrain contains 15mg Pyridoxine HCl, the cheaper, more commonly used form of B6, which is not physiologically active unless it is converted into Pyridoxal in the GI tract.

2. Herbal extracts
ThinkDeep contains polar extracts of grape seed, pine bark, ginkgo leaf, bacopa aerials, and siberian ginseng. The first two consist almost entirely of Oligomeric Proanthocyanidins, which are neuroprotective antioxidants, and the latter three contain a variety of polyphenols, terpenes, and other phytochemicals to which have been attributed a wide range of beneficial effects, the distinctions between which are not presently relevant. My aim was to replicate the neurochemical environment produced by a diet rich in wild fruit, which very few people have access to anymore.

AlphaBrain also contains bacopa monneri extract, although in my view a 500mg dose is perhaps a bit excessive. In addition, it contains extracts of oat straw and cat's claw (which they refer to as "AC11"); the first is touted as an aphrodesiac and anxiolytic, and the latter has been found to repair damage to DNA.

3. Amino Acid Neurotransmitter Precursors
ThinkDeep contains the neurotransmitter precursors 5-HydroxyTryptophan (5-HTP), N-Acetyl Tyrosine (NALT), and Nicotinyl GABA (Picamilon).
5-HydroxyTryptophan enters the central nervous system and is decarboxylated (in a B6-dependent reaction) into serotonin, which may then be metabolized into melatonin, pinoline, and other tryptamine-containing substances.
NALT is a more soluble form of L-Tyrosine, which is the amino acid precursor to dopamine, norepinephrine, epinephrine, and thyroxine.
Picamilion is the amide of Gamma-Amino Butyric Acid (GABA) and nicotinic acid (vitamin B3). Unbound, 'free' GABA does not cross into the brain in significant amounts, although it inhibits cortisol secretion by the adrenal glands. When bound to Niacin (B3) it readily crosses into the brain, where it is cleaved into its components and in addition exhibits beneficial cerebrovascular effects of its own, for which it is used in russia. Niacin (B3) is the precursor to NAD+, a ubiquitous cofactor involve in biological oxidation-reduction reactions.

AlphaBrain contains L-DOPA extracted from Mucuna Puriens. L-DOPA is decarboxylated into dopamine, which may then be metabolized into other catecholamines. Like 5-HTP, it is not incorporated into proteins, and is instead used for neurotransmitter (and melanin) synthesis. For this reason it has been used to treat parkinsons' ataxia, which is thought to be caused by the death of dopaminergic neurons. However, L-DOPA can cause a wide range of adverse peripheral effects, due to its being just one step away from Dopamine, which N-Acetyl-Tyrosine does not. L-DOPA in the form of Mucuna Puriens has been claimed to be less toxic than pure synthetic L-DOPA.
AlphaBrain also contains 200mg of GABA. As previously mentioned, the blood-brain barrier has been found to be impermeable to 'free' GABA, which is normaly synthesized in the brain from glutamine. Any effects felt from taking oral GABA are likely due to its effects on the adrenal cortex.

4. Metabolic Components
ThinkDeep contains R-Alpha Lipoic Acid, Acetyl-L-Carnitine, and Sulbutiamine.
L-Carnitine is a metabolite of Lysine which is responsible for transporting fatty acids into the mitochondria. It is essential for the catabolism of fats, and Acetyl-L-Carnitine is inolved in the synthesis of AcetylCholine. ALCAR has been shown to stimulate regrowth of neural processes, especially following a stroke. Its administration has been found to increase neurotransmitter levels throughout the brain, it enhances mental energy, and it may slow or reverse some markers of brain aging.
Alpha Lipoic Acid is an antioxidant and enzyme cofactor involved in a wide range of biological functions. It is a potent antioxidant that can travel through cells and into the brain, and restores other antioxidants which have been depleted. It induces the excretion of toxic mercury, and may be effective against alzheimer's disease, multiple sclerosis, inflammation, cognitive decline, and more. Alpha Lipoic Acid exists in two enantiomeric (mirror-image) forms: R-ALA, and S-ALA. In living organisms ALA exists entirely in the R form; the S form is largely inactive and may cause adverse effects. Most ALA used in supplements is RS-ALA, which is a mixture of both; pure R-ALA is more expensive but also more bioavailable. Unfortunately, R-ALA has been known to spontaneously polymerize; therefore, ThinkDeep contains stabilized Na-R-ALA, the highest quality (and most expensive) form of ALA.
Sulbutiamine is a bioavailible dimer of Thiamine (B1) which readily crosses into the brain. Sulbutiamine used in the treatment of muscle weakness and fatigue. It improves long term memory in mice and attenuates alzheimers-associated memory impairment by enhaning a variety of neurotransmitter systems in different parts of the brain, including the hippocampus and prefrontal cortex. Thiamine and its phosphorylated derivatives are involved in the synthesis of GABA and Acetylcholine, as well as a variety of essential metabolic reactions.

AlphaBrain contains glyceryl phosphatidyl choline (GPC); this is an ester of Choline, a quaternary amine which is the precursor to the neurotransmitter Acetylcholine. GPC enters the brain and releases choline, which can lead to increased acetylcholine levels.

5. Nootropics

ThinkDeep contains Piracetam and Aniracetam, prototypical 'smart drugs' from the racetam family of compounds. Their effects include, but are not limited to, enhancing glutamatergic and acetylcholinergic transmission, increasing brain activity and oxygen and glucose consumption, reducing lipofuscin levels, protecting against hypoxia and brain trauma, enhancing inter-hemispheral communication, and improving focus and learning. They are remarkably nontoxic, and reports of adverse effects are rare and mild.

AlphaBrain contains Vinpocetine, Pterostilbene, and Huperazine A. In contrast to the racetams, these are potent substances with a relatively narrow dose range.
Vinpocetine is a semi-synthetic alkaloid derived from periwinkle that enhances oxygen uptake, improves recovery after stroke, slows cognitive decline, and protects against excitotoxicity. It has been found to be nontoxic at doses higher than those used in AlphaBrain.
Pterostilbene is a more bioavailable variation of reservatrol, a popular antioxidant sometimes used to prevent cognitive decline. AlphaBrain contains a very small amount of Pterostilbene.
Huperazine A is an alkaloid from the Huperaza Serrata plant which is used in the treatment of alzheimer's and related conditions. It increases levels of acetylcholine by inhibiting an enzyme, acetylcholinesterase, which catabolizes it into choline. This can result in enhanced focus, memory, and mental endurance. It can also result in excess acetylcholine levels, and can interfere with the other functions of acetylcholinesterase. The amount contained in AlphaBrain (250 ug) is very high, similar to the doses used in studies on alzheimers patients. Yes, you will 'feel something', but it's definitely not something you want to take regularly and indiscriminately, and seems rather irresponsible on their part.

I never saw your seller thread. What are the prices for the 3 of your pills? What quantities do you sell them in? and how long will they need to be taken for an effect to be noticed?

Price will start at about 1.50 per capsule, with discounts for larger purchases. A 24 capsule bottle will be about $30, depending on the product. I do custom orders in intervals of 5 capsules. As for the effects, there are both 'acute' effects with one use, and cumulative effects that improve over time.



Hello!

Is taking 5 HTP for MDMA recovery worthwhile and if so is it better to take before or after rolling?

Does Magnesium Oxide really preventing jaw clenching?

Whats a good antioxidant to take after a big weekend?


5-HTP is the precursor to serotonin and other neurotransmitters, so supplementing with it could potentially increase brain levels of them (if you also take B6).

Magnesium alleviates involuntary jaw clenching, but magnesium oxide is the cheapest, least bioavailable form of magnesium and should not be your first choice. MindFood contains the more effective Magnesium Ascorbate, which is magnesium bound to vitamin C.

If you have trouble falling asleep you could try my ChillPill, which may be effective for that purpose.
Title: Re: Nootropic supplements
Post by: fatalz on December 15, 2011, 03:47 am
Thanks for the responses. I would love to try your mindfood and thinkdeep, when will you be selling them again?
At first I was thinking it was expensive, but then I realized I spend twice that on a 30 day bottle of nutritional supplements from gnc lol.
Title: Re: Nootropic supplements
Post by: foxymeow on December 15, 2011, 05:22 am
I have one word for you: Deprenyl (and the newer Rasgelline)

MAO-Bs like Deprenyl and Rasgelline are the most potent nootropics i have ever taken and they GREATLY potentiate other nootropics such as DLPA and L-DOPA.

Rasgelline is magical because it is so much cleaner than Deprenyl. It came out only a couple of years ago (Deprenyl has been around since the 60s).
Title: Re: Nootropic supplements
Post by: Tryptamine on December 15, 2011, 10:57 am
Rasgelline is an irreversible MAO-B inhibitor, which tends to mean it does not de-sorb from the proteins to which it ad-sorbs, a quality I try to avoid in supplements I take.
Deprenyl is a pro-drug for methamphetamine. I don't doubt that these have nootropic effects, but I'm not looking to include this sort of thing in my supplements.
Title: Re: Nootropic supplements
Post by: foxymeow on December 15, 2011, 01:21 pm
Rasgelline is an irreversible MAO-B inhibitor, which tends to mean it does not de-sorb from the proteins to which it ad-sorbs, a quality I try to avoid in supplements I take.
Deprenyl is a pro-drug for methamphetamine. I don't doubt that these have nootropic effects, but I'm not looking to include this sort of thing in my supplements.

Deprenyl being a pro-drug for methamphetamine is a common misconception. The metabolite of Deprenyl is Levo-Methamphetamine which is a mostly inactive version that is the same version that is in Vicks Vapor Sticks (they even commonly mispell it as levo-amphetamine or mfampheatmine just to make it clear that it isn't the same chemical)

Rasgelline is just a reformulation that uses 2-AI as carrier rather than levo-amphetamine.

MAO-B enzymes are constantly being produced in your body. Taking an MAO-B only takes away the MAO-B enzymes that are already in existence. It goes back to the previous levels within 2 weeks of stopping your regiment.

Deprenyl has a loooong history of use as a nootropic and is one of the most well known nootropics.

I myself have used Deprenyl for 6 months and I more recently switched to Rasgelline. Rasgelline has extremely mild stimulation and combines fantasticly with a L-DOPA and L/D Phenylthamine as it prevents your body from blocking those chemicals.

Dopamine oxidation is bad for you and MAO-Bs prevent dopamine oxidation. Think of it as Vitamin C on Crack.

Also Deprenyl destroys addiction. I used to be addicted to amphetamines/molly/anything I could get my hands on. Lately I only do Psychadelics every once in a while and only sell molly.
Title: Re: Nootropic supplements
Post by: crib on December 15, 2011, 06:07 pm
Trypt - THANK YOU for your detailed and thoughtful posts.

I like your style. VERY excited to see these products listed.

I've played with some -racetams and choline before - had results, but not that impressed.

I'm buying the instant it goes up.
Title: Re: Nootropic supplements
Post by: Tryptamine on December 15, 2011, 07:01 pm
Rasgelline is an irreversible MAO-B inhibitor, which tends to mean it does not de-sorb from the proteins to which it ad-sorbs, a quality I try to avoid in supplements I take.
Deprenyl is a pro-drug for methamphetamine. I don't doubt that these have nootropic effects, but I'm not looking to include this sort of thing in my supplements.

Deprenyl being a pro-drug for methamphetamine is a common misconception. The metabolite of Deprenyl is Levo-Methamphetamine which is a mostly inactive version that is the same version that is in Vicks Vapor Sticks (they even commonly mispell it as levo-amphetamine or mfampheatmine just to make it clear that it isn't the same chemical)

Rasgelline is just a reformulation that uses 2-AI as carrier rather than levo-amphetamine.

MAO-B enzymes are constantly being produced in your body. Taking an MAO-B only takes away the MAO-B enzymes that are already in existence. It goes back to the previous levels within 2 weeks of stopping your regiment.

Deprenyl has a loooong history of use as a nootropic and is one of the most well known nootropics.

I myself have used Deprenyl for 6 months and I more recently switched to Rasgelline. Rasgelline has extremely mild stimulation and combines fantasticly with a L-DOPA and L/D Phenylthamine as it prevents your body from blocking those chemicals.

Dopamine oxidation is bad for you and MAO-Bs prevent dopamine oxidation. Think of it as Vitamin C on Crack.

Also Deprenyl destroys addiction. I used to be addicted to amphetamines/molly/anything I could get my hands on. Lately I only do Psychadelics every once in a while and only sell molly.

I did notice that it's the levo form; it's still methamphetamine, the 'inactive' L-met competes with other monoamines for catabolism, which would allow L-DOPA, PEA, etc. to remain 'active' for longer. 

Again, these are potent, irreversible, and potentially toxic chemicals whose effects are not indefinitely sustainable. It's reasonable that it might improve bioavailability of oral L-DOPA, but I don't think that's a reason for a 'healthy' individual to take them regularly.
Title: Re: Nootropic supplements
Post by: hillbilly300 on December 16, 2011, 02:49 am
Hey tryptamine, you need to update your signature thing for your posts the new address is http://silkroadvb5piz3r.onion. Also the other links posted earlier don't work either.
Title: Re: Nootropic supplements
Post by: Zeo on December 16, 2011, 03:05 am
I'm not sure what the appeal is for this. I mean you could just create your own pill using something like cerebral health, this way you get what you want and no need to spend heaps.
Title: Re: Nootropic supplements
Post by: foxymeow on December 16, 2011, 03:53 am
Rasgelline is an irreversible MAO-B inhibitor, which tends to mean it does not de-sorb from the proteins to which it ad-sorbs, a quality I try to avoid in supplements I take.
Deprenyl is a pro-drug for methamphetamine. I don't doubt that these have nootropic effects, but I'm not looking to include this sort of thing in my supplements.

Deprenyl being a pro-drug for methamphetamine is a common misconception. The metabolite of Deprenyl is Levo-Methamphetamine which is a mostly inactive version that is the same version that is in Vicks Vapor Sticks (they even commonly mispell it as levo-amphetamine or mfampheatmine just to make it clear that it isn't the same chemical)

Rasgelline is just a reformulation that uses 2-AI as carrier rather than levo-amphetamine.

MAO-B enzymes are constantly being produced in your body. Taking an MAO-B only takes away the MAO-B enzymes that are already in existence. It goes back to the previous levels within 2 weeks of stopping your regiment.

Deprenyl has a loooong history of use as a nootropic and is one of the most well known nootropics.

I myself have used Deprenyl for 6 months and I more recently switched to Rasgelline. Rasgelline has extremely mild stimulation and combines fantasticly with a L-DOPA and L/D Phenylthamine as it prevents your body from blocking those chemicals.

Dopamine oxidation is bad for you and MAO-Bs prevent dopamine oxidation. Think of it as Vitamin C on Crack.

Also Deprenyl destroys addiction. I used to be addicted to amphetamines/molly/anything I could get my hands on. Lately I only do Psychadelics every once in a while and only sell molly.

I did notice that it's the levo form; it's still methamphetamine, the 'inactive' L-met competes with other monoamines for catabolism, which would allow L-DOPA, PEA, etc. to remain 'active' for longer. 

Again, these are potent, irreversible, and potentially toxic chemicals whose effects are not indefinitely sustainable. It's reasonable that it might improve bioavailability of oral L-DOPA, but I don't think that's a reason for a 'healthy' individual to take them regularly.

Its generally one of the best things for long term motivation. It got me completely off Adderall/Dexedrine. I swear by it. It may seem kind of sketch at first glance but it was one of the most well-tested and documented nootropics, right up there with piracetam.

It greatly reduces neurotoxticity and has long-term benefits. I have been on MAO-Bs for 6 months and I went from a 2.6 to getting all As over the Summer and all As last semester.

The proof is in the pudding, read up on the life extension forum.
Title: Re: Nootropic supplements
Post by: Hardstyle on December 16, 2011, 06:15 am

Its generally one of the best things for long term motivation. It got me completely off Adderall/Dexedrine. I swear by it. It may seem kind of sketch at first glance but it was one of the most well-tested and documented nootropics, right up there with piracetam.

It greatly reduces neurotoxticity and has long-term benefits. I have been on MAO-Bs for 6 months and I went from a 2.6 to getting all As over the Summer and all As last semester.

The proof is in the pudding, read up on the life extension forum.

 I found this is really interesting.  See, I had the same thing happen to me grade wise last semester but that was from STARTING adderall.  I use it both recreationally and for when I needed to work, but I did actually have ADHD and a prescription.  Improved my life two-fold.  What made you want to stop, and are you now taking deprenyl as a substitute? 
Title: Re: Nootropic supplements
Post by: foxymeow on December 16, 2011, 09:08 am
I take Rasgelline now because it has very little stimulation (I don't like stimulation much).

Its not really a substitute, more of me just being able to get work done without being completely cracked out.
Title: Re: Nootropic supplements
Post by: Tryptamine on December 17, 2011, 12:44 am
Rasgelline is an irreversible MAO-B inhibitor, which tends to mean it does not de-sorb from the proteins to which it ad-sorbs, a quality I try to avoid in supplements I take.
Deprenyl is a pro-drug for methamphetamine. I don't doubt that these have nootropic effects, but I'm not looking to include this sort of thing in my supplements.

Deprenyl being a pro-drug for methamphetamine is a common misconception. The metabolite of Deprenyl is Levo-Methamphetamine which is a mostly inactive version that is the same version that is in Vicks Vapor Sticks (they even commonly mispell it as levo-amphetamine or mfampheatmine just to make it clear that it isn't the same chemical)

Rasgelline is just a reformulation that uses 2-AI as carrier rather than levo-amphetamine.

MAO-B enzymes are constantly being produced in your body. Taking an MAO-B only takes away the MAO-B enzymes that are already in existence. It goes back to the previous levels within 2 weeks of stopping your regiment.

Deprenyl has a loooong history of use as a nootropic and is one of the most well known nootropics.

I myself have used Deprenyl for 6 months and I more recently switched to Rasgelline. Rasgelline has extremely mild stimulation and combines fantasticly with a L-DOPA and L/D Phenylthamine as it prevents your body from blocking those chemicals.

Dopamine oxidation is bad for you and MAO-Bs prevent dopamine oxidation. Think of it as Vitamin C on Crack.

Also Deprenyl destroys addiction. I used to be addicted to amphetamines/molly/anything I could get my hands on. Lately I only do Psychadelics every once in a while and only sell molly.

I did notice that it's the levo form; it's still methamphetamine, the 'inactive' L-met competes with other monoamines for catabolism, which would allow L-DOPA, PEA, etc. to remain 'active' for longer. 

Again, these are potent, irreversible, and potentially toxic chemicals whose effects are not indefinitely sustainable. It's reasonable that it might improve bioavailability of oral L-DOPA, but I don't think that's a reason for a 'healthy' individual to take them regularly.

Its generally one of the best things for long term motivation. It got me completely off Adderall/Dexedrine. I swear by it. It may seem kind of sketch at first glance but it was one of the most well-tested and documented nootropics, right up there with piracetam.

It greatly reduces neurotoxticity and has long-term benefits. I have been on MAO-Bs for 6 months and I went from a 2.6 to getting all As over the Summer and all As last semester.

The proof is in the pudding, read up on the life extension forum.

I'm not saying it wouldn't be good for getting off amphetamine, in which case it is a question of pharmacokinetics. It might even be beneficial to take under normal conditions once in a while. But when you take such a thing regularly your biochemistry compensates, and you don't want to be stuck needing to take rasegelline to get back to 'baseline'. I'm not just talking about specific proteins being inactivated, I'm talking about the feedback loops that result from them.
Also, many flavonoids and other phytochemicals have similar (albeit milder) mao-b 'inhibiting' effects, and those you can (and should) take regularly forever.
Title: Re: Nootropic supplements
Post by: foxymeow on December 17, 2011, 02:19 am
Rasgelline is an irreversible MAO-B inhibitor, which tends to mean it does not de-sorb from the proteins to which it ad-sorbs, a quality I try to avoid in supplements I take.
Deprenyl is a pro-drug for methamphetamine. I don't doubt that these have nootropic effects, but I'm not looking to include this sort of thing in my supplements.

Deprenyl being a pro-drug for methamphetamine is a common misconception. The metabolite of Deprenyl is Levo-Methamphetamine which is a mostly inactive version that is the same version that is in Vicks Vapor Sticks (they even commonly mispell it as levo-amphetamine or mfampheatmine just to make it clear that it isn't the same chemical)

Rasgelline is just a reformulation that uses 2-AI as carrier rather than levo-amphetamine.

MAO-B enzymes are constantly being produced in your body. Taking an MAO-B only takes away the MAO-B enzymes that are already in existence. It goes back to the previous levels within 2 weeks of stopping your regiment.

Deprenyl has a loooong history of use as a nootropic and is one of the most well known nootropics.

I myself have used Deprenyl for 6 months and I more recently switched to Rasgelline. Rasgelline has extremely mild stimulation and combines fantasticly with a L-DOPA and L/D Phenylthamine as it prevents your body from blocking those chemicals.

Dopamine oxidation is bad for you and MAO-Bs prevent dopamine oxidation. Think of it as Vitamin C on Crack.

Also Deprenyl destroys addiction. I used to be addicted to amphetamines/molly/anything I could get my hands on. Lately I only do Psychadelics every once in a while and only sell molly.

I did notice that it's the levo form; it's still methamphetamine, the 'inactive' L-met competes with other monoamines for catabolism, which would allow L-DOPA, PEA, etc. to remain 'active' for longer. 

Again, these are potent, irreversible, and potentially toxic chemicals whose effects are not indefinitely sustainable. It's reasonable that it might improve bioavailability of oral L-DOPA, but I don't think that's a reason for a 'healthy' individual to take them regularly.

Its generally one of the best things for long term motivation. It got me completely off Adderall/Dexedrine. I swear by it. It may seem kind of sketch at first glance but it was one of the most well-tested and documented nootropics, right up there with piracetam.

It greatly reduces neurotoxticity and has long-term benefits. I have been on MAO-Bs for 6 months and I went from a 2.6 to getting all As over the Summer and all As last semester.

The proof is in the pudding, read up on the life extension forum.

I'm not saying it wouldn't be good for getting off amphetamine, in which case it is a question of pharmacokinetics. It might even be beneficial to take under normal conditions once in a while. But when you take such a thing regularly your biochemistry compensates, and you don't want to be stuck needing to take rasegelline to get back to 'baseline'. I'm not just talking about specific proteins being inactivated, I'm talking about the feedback loops that result from them.
Also, many flavonoids and other phytochemicals have similar (albeit milder) mao-b 'inhibiting' effects, and those you can (and should) take regularly forever.

I do cycle now. I only take it during the week particularly when I have a paper to do or have finals/midterm.

I feel the same way about piracetam. I used to take 3g of Piracetam twice a day.

BTW I just ordered a KG of aniracetam and 100g Oxiracetam...I'm so excited for getting that package next semester and using it for school...wait what?
Title: Re: Nootropic supplements
Post by: Tryptamine on December 19, 2011, 07:29 pm
Update: Listings will be up this week, probably by wednesday.
Title: Re: Nootropic supplements
Post by: Holly on December 21, 2011, 09:06 pm
Come on brah quit holding out on us!!
Title: Re: Nootropic supplements
Post by: crib on December 21, 2011, 10:06 pm
Come on brah quit holding out on us!!
Second this! BTC is falling!
Title: Re: Nootropic supplements
Post by: Tryptamine on December 22, 2011, 06:57 am
Listings will be up tomorrow.
Title: Re: Nootropic supplements
Post by: foxymeow on December 22, 2011, 10:03 pm
I now have new and improved MindFood capsules in stock; they now contain sulbutiamine, a modified dimer of thiamine (B1) that goes straight to the brain, and rhodiola rosea, an adaptogenic and endurance-boosting herb. I plan to have the first version of a 'smart pill' out probably next week, if not earlier.

Dude those sound pretty legit.

Sulbutiamine is totally legit. Do you have any erogloids or pharmaceutical nootropics?
Title: Re: Nootropic supplements
Post by: Tryptamine on December 23, 2011, 10:02 am
MINDFOOD 5-PACKS NOW FOR SALE

ChillPills and ThinkDeeps will follow within the next couple days.

Get them while they last!





I now have new and improved MindFood capsules in stock; they now contain sulbutiamine, a modified dimer of thiamine (B1) that goes straight to the brain, and rhodiola rosea, an adaptogenic and endurance-boosting herb. I plan to have the first version of a 'smart pill' out probably next week, if not earlier.

Dude those sound pretty legit.

Sulbutiamine is totally legit. Do you have any erogloids or pharmaceutical nootropics?

I'm trying to stick to things with a very wide dosage range, to prevent adverse effects or drug interactions. I might consider some more potent compounds for subsequent products.
Title: Re: Nootropic supplements
Post by: foxymeow on December 23, 2011, 02:42 pm
MINDFOOD 5-PACKS NOW FOR SALE

ChillPills and ThinkDeeps will follow within the next couple days.

Get them while they last!





I now have new and improved MindFood capsules in stock; they now contain sulbutiamine, a modified dimer of thiamine (B1) that goes straight to the brain, and rhodiola rosea, an adaptogenic and endurance-boosting herb. I plan to have the first version of a 'smart pill' out probably next week, if not earlier.

Dude those sound pretty legit.

Sulbutiamine is totally legit. Do you have any erogloids or pharmaceutical nootropics?

I'm trying to stick to things with a very wide dosage range, to prevent adverse effects or drug interactions. I might consider some more potent compounds for subsequent products.

I hear you. If you need any racetams in bulk, I'll give em to you at/near cost. Because everyone should have nootropics!
Title: Re: Nootropic supplements
Post by: crib on December 23, 2011, 05:51 pm
MINDFOOD 5-PACKS NOW FOR SALE

ChillPills and ThinkDeeps will follow within the next couple days.

Get them while they last!
Damn, did I miss them!? Was watching all day yesterday, don't see any listings now
Title: Re: Nootropic supplements
Post by: Tryptamine on December 23, 2011, 06:17 pm
MINDFOOD 5-PACKS NOW FOR SALE

ChillPills and ThinkDeeps will follow within the next couple days.

Get them while they last!
Damn, did I miss them!? Was watching all day yesterday, don't see any listings now
I guess the item didn't update, it's there now.
Title: Re: Nootropic supplements
Post by: fatalz on December 24, 2011, 04:23 am
Ordered a 5 pack of mindfood to sample them :)

might want to update the link in this listing with the new SR link
http://silkroadvb5piz3r.onion/index.php/silkroad/item/5668

Im gonna order some thinkdeep's also whenver you get them available.
Title: Re: Nootropic supplements
Post by: Tryptamine on December 26, 2011, 06:55 am
The new ThinkDeeps are still undergoing testing, but I have some of the 1.1 version that I could sell right now. I just listed them.
The new ones will be up within the next couple of days.
Title: Re: Nootropic supplements
Post by: k4rts on December 30, 2011, 03:46 am
Anyone who has taken these supplements..would you mind sharing your experience with them? How did they make you feel after 1 dose? 5 doses?
Title: Re: Nootropic supplements
Post by: fatalz on December 30, 2011, 04:01 am
Anyone who has taken these supplements..would you mind sharing your experience with them? How did they make you feel after 1 dose? 5 doses?

I'll be sharing my experiences once they arrive. I will be testing out the thinkdeep and mindfood.
Title: Re: Nootropic supplements
Post by: Holly on December 30, 2011, 05:55 am
Just ordered 2 bottles of mindfood and a bottle of thinkdeep.... I love throwing money at tryptamine :P
Title: Re: Nootropic supplements
Post by: Tryptamine on December 30, 2011, 10:30 pm
Anyone who has taken these supplements..would you mind sharing your experience with them? How did they make you feel after 1 dose? 5 doses?

I have a review thread; it's kind of sparse, but I'm hoping it'll grow now. I also have a couple reviews in my seller feedback somewhere as well.
http://dkn255hz262ypmii.onion/index.php?topic=3299

Just ordered 2 bottles of mindfood and a bottle of thinkdeep.... I love throwing money at tryptamine :P

And I love catching it.
Title: Re: Nootropic supplements
Post by: crib on December 31, 2011, 12:22 am
Got my order today, thanks Trypt

Just popped 2 mindfoods, I'll be sure to report the thoughts of myself and a few other test subjects when available.

EDIT-- wanted to report that I had fairly vivid dreams last night, and I almost NEVER dream (or remember it, I guess is the right way to say it). Not to say that the mindfoods are certainly the cause, as I had a lot in my system last night.. :)
Title: Re: Nootropic supplements
Post by: Tryptamine on January 08, 2012, 01:38 am
New ChillPills now available!

From the item description:

Quote
A blend of nootropics, herbal extracts, and vitamins designed to promote relaxation, attenuate stress, boost neurotransmitter levels, improve the quality and onset of sleep, and enhance dreaming.

Don't waste your money on toxic and expensive 'sleep aids', opiates, or benzos; try this nontoxic, nonaddictive alternative first.

Contains:

Valerian Root Extract
L-Theanine (N-Ethyl-Glutamine)
Magnesium Ascorbate (Vitamin C)
Picamilon (GABA bound to Naicin [B3])
5-Hydroxy-Tryptophan (5-HTP)
Grape Seed Extract (99% Oligomeric Proanthocyanidins)
Pine Bark Extract (98% Oligomeric Proanthocyanidins)
Ginkgo Biloba Extract (24% Ginkgolides)
Pyridoxal-5-Phosphate (Vitamin B6)

HydroxyPropylMethylCellulose
Bioperine

Take one when you want to relax, sleep, and/or dream.

Got my order today, thanks Trypt

Just popped 2 mindfoods, I'll be sure to report the thoughts of myself and a few other test subjects when available.

EDIT-- wanted to report that I had fairly vivid dreams last night, and I almost NEVER dream (or remember it, I guess is the right way to say it). Not to say that the mindfoods are certainly the cause, as I had a lot in my system last night.. :)

That may have been from the P5P, the ginkgo, and/or the ALCAR. Try the ChillPills if you want to dream.
Title: Re: Nootropic supplements
Post by: Tryptamine on February 05, 2012, 05:48 pm
More ChillPills now available, now with Piperine for enhanced bioavilablity.
Title: Re: Nootropic supplements
Post by: 72289 on February 07, 2012, 02:09 am
Sent you a PM with a few questions.  Can't wait to try it after I get the answers. :D
Title: Re: Nootropic supplements
Post by: 72289 on February 07, 2012, 01:44 pm
Just ordered a 24 pack of the Chill Pills. :) Super excited
Title: Re: Nootropic supplements
Post by: Holly on February 08, 2012, 01:52 am
Just ordered a 24 pack of the Chill Pills. :) Super excited

They definitely are splendid!  Use them everyday.
Title: Re: Nootropic supplements
Post by: jerichodotm on February 09, 2012, 03:12 pm
I'm very interested in this topic.  As I "mature", my energy, memory and concentration get worse and worse.
Title: Re: Nootropic supplements
Post by: werfelGB on February 20, 2012, 07:57 pm
Hey Tryptamine, will you be listing more ChillPills or ThinkDeep's in the future?  I've been reading a lot about them and I'm very interested!  Also just wanted to say that I'm very impressed, you seem to be a knowledgeable person about this and it's awesome that you offer these things to people here. Thanks  :)
Title: Re: Nootropic supplements
Post by: Tryptamine on March 02, 2012, 05:23 pm
New batch of MindFood (3.0) ThinkDeep (2.4) and ChillPill (2.3) now available. Get them while they last.

http://silkroadvb5piz3r.onion/silkroad/user/5339
Title: Re: Nootropic supplements
Post by: Holly on March 13, 2012, 05:58 am
Anyone using the ThinkDeeps?
Title: Re: Nootropic supplements
Post by: l1llykins on March 13, 2012, 06:14 am
Ordered a sample of mind food, hoping it helps me feel less tired after my roll in a few weeks!
Title: Re: Nootropic supplements
Post by: werfelGB on March 14, 2012, 04:33 am
Ordered a sample of mind food, hoping it helps me feel less tired after my roll in a few weeks!

I haven't used one post-roll (yet), but they made me feel pretty good both times I took a pill, so I think they will help a lot afterwards. 
Title: Re: Nootropic supplements
Post by: l1llykins on March 14, 2012, 04:36 am
Ordered a sample of mind food, hoping it helps me feel less tired after my roll in a few weeks!

I haven't used one post-roll (yet), but they made me feel pretty good both times I took a pill, so I think they will help a lot afterwards.

Tryp recommends taking it a few hours before a roll. I'll be adding it to my preloading regimen if all goes well.
Title: Re: Nootropic supplements
Post by: l1llykins on March 22, 2012, 06:08 am
I was suffering from major brain fog from trying too large a dose of edibles last night. I decided to take a mind food pill around lunch and it helped so much! My body is still achy but my mind cleared right up, it was amazing.

I think I'll be getting a full bottle now.
Title: Re: Nootropic supplements
Post by: CX on March 22, 2012, 07:09 am
Tried a chill pill the other night. Had a great sleep. Won't be taking benzos ever again!
Title: Re: Nootropic supplements
Post by: minorthreat71 on March 23, 2012, 12:07 pm
what's in your "smart pill" plan?
if { Piracetam? Oxiracetiam? Ani? Pram?
   Why sell on SR
else { What is the active ingredient?

Will it be instant or will redosing be needed to achieve a noticeable effect?
yep
Title: Re: Nootropic supplements
Post by: Tryptamine on March 24, 2012, 12:38 am
what's in your "smart pill" plan?
if { Piracetam? Oxiracetiam? Ani? Pram?
   Why sell on SR
else { What is the active ingredient?

Will it be instant or will redosing be needed to achieve a noticeable effect?
yep

?
Title: Re: Nootropic supplements
Post by: l1llykins on March 25, 2012, 06:51 am
What's up Tryp? I've been in processing since Wednesday.
Title: Re: Nootropic supplements
Post by: Holly on March 25, 2012, 02:40 pm
Same.  He's out of stock but he should be getting more fairly soon(couple days) he says.
Title: Re: Nootropic supplements
Post by: l1llykins on March 26, 2012, 08:04 pm
Ok sounds good :).
Title: Re: Nootropic supplements
Post by: Tryptamine on April 20, 2012, 05:20 pm
Sending out free samples with every order for the holidays, plus 10% off!
Title: Re: Brain-Enhancing Supplements (free samples with every order during 4/20 sale)
Post by: poolsclosed on May 07, 2012, 02:58 am
I suffer from narcolepsy and I take Adderall daily to stay awake. While I love the boost I get from Adderall I've grown to hate the stimulation. I'm interested in seeing whether your supplements will have a beneficial effect on my wakefulness. I'm also interested to see if chillpills will have a beneficial or possibly negative effect on my sleep patterns.

Do you have a professional opinion on the use of your supplements in a narcoleptic patient?
Title: Re: Brain-Enhancing Supplements
Post by: Tryptamine on May 07, 2012, 03:50 am
ThinkDeep and to a lesser extent MindFood would increase your level of arousal; ChillPill has the opposite effect, although the increase in sleep quality that it provides may address some of the causes of the narcolepsy. I'm currently in the early stages of developing a natural, sustainable 'stimulant' capsule, although that won't be available for a while.
Title: Re: Brain-Enhancing Supplements
Post by: poolsclosed on May 07, 2012, 03:53 am
ThinkDeep and to a lesser extent MindFood would increase your level of arousal; ChillPill has the opposite effect, although the increase in sleep quality that it provides may address some of the causes of the narcolepsy. I'm currently in the early stages of developing a natural, sustainable 'stimulant' capsule, although that won't be available for a while.
I see. Given the fact that I take 5-HTP and melatonin right before bed every night and it helps to regulate my sleep and make it easier for me to wake in the morning, I may be able to benefit from your ChillPill. I suppose it's worth a shot, right?

Since you don't have ThinkDeep listed should I not order the sample pack yet?
Title: Re: Brain-Enhancing Supplements
Post by: Tryptamine on May 07, 2012, 04:02 am
ThinkDeep and to a lesser extent MindFood would increase your level of arousal; ChillPill has the opposite effect, although the increase in sleep quality that it provides may address some of the causes of the narcolepsy. I'm currently in the early stages of developing a natural, sustainable 'stimulant' capsule, although that won't be available for a while.
I see. Given the fact that I take 5-HTP and melatonin right before bed every night and it helps to regulate my sleep and make it easier for me to wake in the morning, I may be able to benefit from your ChillPill. I suppose it's worth a shot, right?

Since you don't have ThinkDeep listed should I not order the sample pack yet?

That's right. I'll have it listed sometime this week.

If you take ChillPill, don't take extra 5-HTP, although melatonin would still be effective.
Title: Re: Brain-Enhancing Supplements
Post by: poolsclosed on May 07, 2012, 04:07 am
ThinkDeep and to a lesser extent MindFood would increase your level of arousal; ChillPill has the opposite effect, although the increase in sleep quality that it provides may address some of the causes of the narcolepsy. I'm currently in the early stages of developing a natural, sustainable 'stimulant' capsule, although that won't be available for a while.
I see. Given the fact that I take 5-HTP and melatonin right before bed every night and it helps to regulate my sleep and make it easier for me to wake in the morning, I may be able to benefit from your ChillPill. I suppose it's worth a shot, right?

Since you don't have ThinkDeep listed should I not order the sample pack yet?

That's right. I'll have it listed sometime this week.

If you take ChillPill, don't take extra 5-HTP, although melatonin would still be effective.
Of course. I've been through mild serotonin syndrome and it's sure shitty! (pun intended.) Unless ChillPill contains 100mg of 5-HTP, though, I'd probably cover the difference since that is how much I regularly take. Unless this is a poor idea? The 5-HTP is meant to be a mood booster in my case rather than a sleep aid; I take it in conjunction with lamotrigine in treatment of cyclothemia/bipolar II.
Title: Re: Brain-Enhancing Supplements
Post by: Tryptamine on May 07, 2012, 04:39 am
5-HTP is an amino acid; its use has innumberable effects on all aspects of physiology, and in a general sense it (and serotonin) has a sensitizing effect on most cells, associated with stress, hypothyroidism, and aging. Most people already get higher-than-necessary amounts from their diets; muscle meat, most people's main source of protein, is high in tryptophan and low in glycine, which counteracts the excitatory effects of tryptophan/5HTP/serotonin. It's not something that typically needs to be supplemented, and I'm actually reducing the amount of 5-HTP in the ChillPill from 60mg to 30mg in the next batch, and adding some trimethylglycine as a glycine (and methyl) source.
Title: Re: Brain-Enhancing Supplements
Post by: poolsclosed on May 07, 2012, 10:16 am
5-HTP is an amino acid; its use has innumberable effects on all aspects of physiology, and in a general sense it (and serotonin) has a sensitizing effect on most cells, associated with stress, hypothyroidism, and aging. Most people already get higher-than-necessary amounts from their diets; muscle meat, most people's main source of protein, is high in tryptophan and low in glycine, which counteracts the excitatory effects of tryptophan/5HTP/serotonin. It's not something that typically needs to be supplemented, and I'm actually reducing the amount of 5-HTP in the ChillPill from 60mg to 30mg in the next batch, and adding some trimethylglycine as a glycine (and methyl) source.
Yeah, I realize this, but unfortunately I'm one of the few who experiences a lot of benefit from 5-HTP. Taking it has definitely, without a doubt, improved my mood tremendously. Thanks for the dosing info, it will help me to keep my regimen more stable :)
Title: Re: Brain-Enhancing Supplements
Post by: Tryptamine on May 10, 2012, 05:01 am
ThinkDeeps back in stock.
Title: Re: Brain-Enhancing Supplements
Post by: LSDANK on May 10, 2012, 11:10 pm
Ordered a mindfood bottle last sunday, eagerly awaiting to try them out! Will report later when they arrive
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on May 17, 2012, 12:56 am
MindFoods back in stock. First version of a new lucid dreaming pill will be available in limited quantities within the next 2 weeks.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: 16384 on May 17, 2012, 02:02 am
Any idea what the expiration date would be on one of these guys?
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Delta11 on May 17, 2012, 05:30 pm
I got some of the chill pills and I love them! I'm moving on to the next ones now see how I like them.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: herbaman on May 24, 2012, 03:15 pm
Can mind food be used to ease comedowns after a benzo trip?
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on May 24, 2012, 09:49 pm
Hello Typtamine!
I am a regular MDMA user (taking about 300mg of dutch mdma every saturday) and I do not take any supplements. I know for a fact my serrotonine is depleted but would like to somewhat help my body. which of your products would you recommend for me?

MindFood beforehand, ChillPill after.

http://silkroadvb5piz3r.onion/silkroad/item/4eb0d69886
http://silkroadvb5piz3r.onion/silkroad/item/4dc5679867
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: poolsclosed on May 24, 2012, 09:54 pm
Hello Typtamine!
I am a regular MDMA user (taking about 300mg of dutch mdma every saturday) and I do not take any supplements. I know for a fact my serrotonine is depleted but would like to somewhat help my body. which of your products would you recommend for me?
Since I'm sleep deprived and in a cranky mood, I'm going to relish the opportunity to be the first to say congratulations, you've done irreparable damage to your serotonin receptors and you have made yourself retarded! It's not depletion to worry about, my friend, it's the damage you're doing to your neurons. You better stop taking MDMA more often than once a month.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: LSDANK on May 24, 2012, 10:38 pm
Received the MindFood in good timing and good packaging. Have been taking the mind food every day.  Feels very nice definitely increasing my mental energy and have had better cognitive thinking so far. Thanks Tryptamine!
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on May 24, 2012, 10:49 pm
Hello Typtamine!
I am a regular MDMA user (taking about 300mg of dutch mdma every saturday) and I do not take any supplements. I know for a fact my serrotonine is depleted but would like to somewhat help my body. which of your products would you recommend for me?
Since I'm sleep deprived and in a cranky mood, I'm going to relish the opportunity to be the first to say congratulations, you've done irreparable damage to your serotonin receptors and you have made yourself retarded! It's not depletion to worry about, my friend, it's the damage you're doing to your neurons. You better stop taking MDMA more often than once a month.

There's no such thing as irreperable damage to serotonin receptors; 'serotonin receptors' are nothing more than certain sites on certain proteins which bind, among other things, serotonin. Adsorption of MDMA would not damage the proteins, although it may lead to lower amounts of them by interfering with feedback loops. As for making himself retarded, the only reasonably well conducted study on MDMA use in humans showed no cognitive impairment as a result of long term use (DOI: 10.1111/j.1360-0443.2010.03252.x). I would agree that the dosage he used is excessive, and potentially dangerous; on the other hand, most people (including users) tend to overestimate the risk of MDMA use, as I believe you did in your response.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: poolsclosed on May 25, 2012, 04:35 am
Hello Typtamine!
I am a regular MDMA user (taking about 300mg of dutch mdma every saturday) and I do not take any supplements. I know for a fact my serrotonine is depleted but would like to somewhat help my body. which of your products would you recommend for me?
Since I'm sleep deprived and in a cranky mood, I'm going to relish the opportunity to be the first to say congratulations, you've done irreparable damage to your serotonin receptors and you have made yourself retarded! It's not depletion to worry about, my friend, it's the damage you're doing to your neurons. You better stop taking MDMA more often than once a month.

There's no such thing as irreperable damage to serotonin receptors; 'serotonin receptors' are nothing more than certain sites on certain proteins which bind, among other things, serotonin. Adsorption of MDMA would not damage the proteins, although it may lead to lower amounts of them by interfering with feedback loops. As for making himself retarded, the only reasonably well conducted study on MDMA use in humans showed no cognitive impairment as a result of long term use (DOI: 10.1111/j.1360-0443.2010.03252.x). I would agree that the dosage he used is excessive, and potentially dangerous; on the other hand, most people (including users) tend to overestimate the risk of MDMA use, as I believe you did in your response.
Was the study retrospective? Did it involve frequent, heavy use? I think people overestimate the risk too as reasonable use of MDMA is perfectly safe, but I've seen e-tardation happen to friends and acquaintances, so unless there's another reason (other recreational drug use I didn't know of, just damage from staying up and stressing the body so much), there's all the reason in the world to be careful. I'd like to know more about the study and the topic at large.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on May 25, 2012, 05:31 am
Hello Typtamine!
I am a regular MDMA user (taking about 300mg of dutch mdma every saturday) and I do not take any supplements. I know for a fact my serrotonine is depleted but would like to somewhat help my body. which of your products would you recommend for me?
Since I'm sleep deprived and in a cranky mood, I'm going to relish the opportunity to be the first to say congratulations, you've done irreparable damage to your serotonin receptors and you have made yourself retarded! It's not depletion to worry about, my friend, it's the damage you're doing to your neurons. You better stop taking MDMA more often than once a month.

There's no such thing as irreperable damage to serotonin receptors; 'serotonin receptors' are nothing more than certain sites on certain proteins which bind, among other things, serotonin. Adsorption of MDMA would not damage the proteins, although it may lead to lower amounts of them by interfering with feedback loops. As for making himself retarded, the only reasonably well conducted study on MDMA use in humans showed no cognitive impairment as a result of long term use (DOI: 10.1111/j.1360-0443.2010.03252.x). I would agree that the dosage he used is excessive, and potentially dangerous; on the other hand, most people (including users) tend to overestimate the risk of MDMA use, as I believe you did in your response.
Was the study retrospective? Did it involve frequent, heavy use? I think people overestimate the risk too as reasonable use of MDMA is perfectly safe, but I've seen e-tardation happen to friends and acquaintances, so unless there's another reason (other recreational drug use I didn't know of, just damage from staying up and stressing the body so much), there's all the reason in the world to be careful. I'd like to know more about the study and the topic at large.

Some of the people studied were frequent heavy users. I posted the DOI of the study in the post you quoted. Unlike previous studies, it compared MDMA-only users (other studies did not control for polydrug use) with non-MDMA users who also frequently attended raves (to control for the effects of dancing for hours on end while only drinking water). This was the largest study done on MDMA users, as far as I know. It found no significant neurocognitive impairment in the MDMA-only users. That doesn't say much about neurological effects, but at least indicates that MDMA use alone does not make you 'retarded'.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: poolsclosed on May 25, 2012, 08:56 am
Well, in light of that I actually have to retract my opinion. I believe that's good enough evidence.

I'll still practice harm reduction of course... perhaps there's some other dangers than the dulling of the intellect. But it's actually good to know that. Thank you.

And CaliforniaBuddy, I apologize for insulting you and for being generally a jerk. Like I said I was sleep deprived and cranky, but that's not really a good excuse for acting that way, especially when I'm misinformed.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: herbaman on May 25, 2012, 03:41 pm
Can mind food be used to ease comedowns after a benzo trip?

Tried it loved it.
Interacts and enhances the clarity realm.
Prevents the forget loop which occurs in benzos.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on May 28, 2012, 05:21 pm
ThinkDeep 2.6 now available!
Now with
-Noopept!
-TMG!
-No 5-HTP!
-Improved label!

http://silkroadvb5piz3r.onion/silkroad/item/44558c6f44
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on May 30, 2012, 05:48 pm
Also, a note about the summer: continuously high humidity can cause the capsules to adsorb water. In MindFoods, which have clear gel capsules,  This does not represent any sort of degradation, only the adsorption of water, which happens anyway once you eat them.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Horizons on June 06, 2012, 01:15 pm
My sample of five ChillPills just arrived! (after a slight delay which, based on past experience, I blame entirely on the postal system)
It seems silly to be excited for sleep, but I can't wait to try them out tonight. I always have trouble sleeping when I'm stressed at work like I've been lately, and mainstream pharmaceuticals either don't work or knock me out cold, making me wake up groggy and still tired the next morning.

How long before going to bed should I take these, Tryp?
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Kappacino on June 06, 2012, 05:01 pm
I can personally vouch that mindfood help A LOT with mdma comedown.

How did the lucid dreaming pills turn out?
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: l1llykins on June 06, 2012, 07:01 pm
He ended up making a more potent chill pill with it. But if you combine a think deep with a chill pill you'll basically get what he was going for with the lucid dreaming pill.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on June 06, 2012, 09:23 pm
My sample of five ChillPills just arrived! (after a slight delay which, based on past experience, I blame entirely on the postal system)
It seems silly to be excited for sleep, but I can't wait to try them out tonight. I always have trouble sleeping when I'm stressed at work like I've been lately, and mainstream pharmaceuticals either don't work or knock me out cold, making me wake up groggy and still tired the next morning.

How long before going to bed should I take these, Tryp?

About half an hour to 45 minutes. You can take them earlier, though, since they won't force you to sleep.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Horizons on June 09, 2012, 07:53 pm
Wow, Tryp. Amazing. Your Chill Pills are truly amazing. I'm in love with them.

I took one last night, and I had taken another two nights before. I definitely slept better, felt better rested, and had much more vivid dreams. It's true what you said about the pills not forcing you to sleep as well: though I fell asleep very easily, the pills didn't make me any more drowsy or tired like Ambien does. Also, unlike Ambien, they don't give me an early-morning hangover.

They are the best sleep aid I have ever used, and I've tried several over the years. Every single one so far (even the ones that didn't even work) has had annoying side-effects, but your Chill Pills don't seem to have any at all.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on June 12, 2012, 06:20 am
New ChillPill 3.0 capsules now available!

-No more Vitamin C! (Took up too much space in the capsule, but you should still take it!)
-No more 5-HTP! (It's bad for you and you shouldn't take it!)
-TriMethylGlycine!
-Noopept!
-More herbs! (valerian, damiana, wild lettuce, holy basil, blue vervain, & passion flower extracts)
-They smell great!
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: poolsclosed on June 12, 2012, 01:27 pm
New ChillPill 3.0 capsules now available!

-No more Vitamin C! (Took up too much space in the capsule, but you should still take it!)
-No more 5-HTP! (It's bad for you and you shouldn't take it!)
-TriMethylGlycine!
-Noopept!
-More herbs! (valerian, damiana, wild lettuce, holy basil, blue vervain, & passion flower extracts)
-They smell great!
I wanted to talk to you about 5-HTP. I'm coming off it because I plan on having a DXM trip soon and I wanted to ask you if I should taper or just stop. Depending on the results I may stop taking 5-HTP regularly, although I do still feel that taking 5-HTP regularly helps me.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on June 12, 2012, 04:53 pm
I think it would be fine to just stop, unless you take a large dose frequently.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on June 13, 2012, 01:50 am
New MindFood 3.0 capsules now available!

-Green Capsules!
-More TMG!
-NooPept!
-Now with Holy Basil!
-They smell pretty good!
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: stclemens9 on July 02, 2012, 12:27 am
Hey Tryptamine,
Interested in MindFood and ThinkDeep, but I can't find seem to find them on SR. Are they available currently?
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on July 04, 2012, 06:28 am
I'm currently on vacation, I'll have them for sale once I get back.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: spinbox1 on July 04, 2012, 10:18 am
Wait, so now 5HTP is bad for you?  That has to be the #1 supplement people take before/after MDMA.  I can understand not needing it on a regular day since you'll get it from food, but what about taking before or after MDMA to help recovery?

Tryptamine, what do you think about pre-loading an MDMA trip with an MAOI-B or COX Inhibiter?  I was reading about them here: http://www.mdma.net/kobie/simple.html.

And are SRIs on the comedown neuroprotective?  I've never tried this before either.  I usually take a 5HTP and Melatonin.  I'm gonna try taking your chill pills on my next MDMA comedown.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on July 04, 2012, 05:08 pm
Wait, so now 5HTP is bad for you?  That has to be the #1 supplement people take before/after MDMA.  I can understand not needing it on a regular day since you'll get it from food, but what about taking before or after MDMA to help recovery?

People take fish and flax oil, thinking it's good for them. People supplement with glutamate and aspartate, thinking it's good for them and not excitotoxic. People take SSRIs, hoping that a synthetic drug can somehow 'cure' their 'depression'. People take estrogen, thinking it'll attenuate menopause. People use fluoridated toothpaste and drink fluoridated water, thinking it won't damage their teeth, bones, and brain. People take iron, calcium carbonate (ground up sea shells), L-DOPA, and countless other supplements which are nearly always more harmful than beneficial. There is an immense amount of disinformation related to supplements, and one should keep in mind that 100 years ago the fashion was calomel (mercurous chloride) radium suppositories. The more things change, the more they stay the same.

5-HTP is excitatory, anti-metabolic, stress-promoting (growth-hormone, prolactin, and cortisol-releasing) pro-inflammatory, potentially carcinogenic monoamine. It is released from platelets and mast cells in response to injury or stress, promoting the constriction of blood vessels and formation of clots. In light of this, most substances that produce a stress response are 'serotonin reuptake inhibitors' which decrease its intracellular concentration and cause it to be released. Its energy-suppressing properties are associated with a variety of chronic energy-related diseases, as well as hibernation.

One of the primary ways by which drugs like psilocin and LSD can so profoundly expand our consciousness is by antagonizing or decreasing the activity of serotonin, which itself has the opposite properties than those that are typically ascribed to it. Psychedelic drugs do not work merely by increasing the activity of serotonin; generally speaking, they replace it in binding sites on proteins, and exert slightly different electronic effects on the protein, which alters its electronic environment, an effect which can potentially be propagated indefinitely. Serotonin is 'released' because its place has been taken by MDMA, and when it diffuses out of the cell it is prone to being metabolized. It may interact with nearby cells, but the characteristic effects of psychedelics  are due to their specific electronic effects, not just the endogenous monoamines which they displace. Serotonin's subjective effects include tropor, helplessness, tranquilization, migraine, and apathy. SSRIs drastically increase the risk of suicide in people who take them, probably for this reason.

Most people's diets contain high levels of tryptophan as well, from muscle meat, fish, dairy, soy, and some vegetables. During infancy and childhood it promotes growth, but during adulthood it is potentially carcinogenic and inhibits differentiation. So supplementing with 5-HTP in the vast majority of cases is harmful in the long term, although the acute effects can vary widely depending on how it's utilized and how your body compensates for its consumption.

Quote
Tryptamine, what do you think about pre-loading an MDMA trip with an MAOI-B or COX Inhibiter?  I was reading about them here: http://www.mdma.net/kobie/simple.html.

I don't agree with some of what he says; for example, that cells are surrounded by a 'plasma membrane' embedded with 'transporters' and 'channels' (a reductionist model that was conclusively disproven over 50 years ago). That said, what he says about 5-HTP competing with pro-oxidant MDMA metabolites for entry into serotonergic neurons sounds feasible, although 5-HTP itself is potentially neurotoxic.

Oxidative damage, one of the two major causes of neurotoxicity, can be substantially attenuated by the consumption of antioxidant vitamins and flavonoids, as well as pro-metabolic substances that direct the oxygen towards respiration and away from inappropriate oxidation targets. Things like fish oil flax oil, and iron are highly pro-oxidant since each molecule of DHA and EHA contains 6 double bonds that can be peroxidated in a reaction that may be catalyzed by iron (this is the main form of oxidative damage). Taking these will generally exacerbate oxidative stress and suppress oxidative metabolism, increasing the likelihood of neurotoxicity.
Many herbs and vitamins are themselves COX inhibitors (for example: Vitamin C, Oligomeric Proanthocyanidins, Alpha Lipoic Acid, Sulbutiamine (if thiamine is deficient), TMG, Pyridoxal (B6),  Naicin (B3), Ginkgo, Rhodiola, Bacopa, Holy Basil, and countless others). MindFood contains all of these; ThinkDeep and ChillPill contain many of them. I would not recommend taking a pharmaceutical drug specifically to inhibit COX; no metabolic process exists in a vacuum, and targeting that specific enzyme with a potent, specific drug will invariably cause imbalances elsewhere. If you really want to go that route, perhaps you could try white willow bark extract, which was the natural inspiration for the less effective and more toxic drug Aspirin.

Quote
And are SRIs on the comedown neuroprotective?  I've never tried this before either.  I usually take a 5HTP and Melatonin.  I'm gonna try taking your chill pills on my next MDMA comedown.

Possibly; however I would not recommend anyone take pharmaceutical SSRIs, ever. Either way, preventing oxidative damage is far more important and non-invasive, and may be at odds with the effects of the SSRIs, which are not necessarily anything more than patented toxins.
My ChillPills contain neither 5-HTP nor melatonin, although the latter may be beneficial to take from time to time.

Bottom line: stop taking pro-oxidant, anti-metabolic substances (iron, PUFA oils (fish, flax, soy, sunflower), 5-HTP/serotonin, amphetamines, glutamate/aspartate), start taking anti-oxidant, pro-metabolic substances (the ones I listed earlier, as well as coconut oil to replace the aforementioned polyunsaturated fat oils), and you can generally prevent neurotoxicity without pushing your metabolism unsustainably in one direction. Metabolism is far more interconnected and fundamental than the membrane/receptor/pump/channel/transporter model implies.

That was a pretty long post. Hopefully a lot of people read it.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Delta11 on July 04, 2012, 08:57 pm
Wait, so now 5HTP is bad for you?  That has to be the #1 supplement people take before/after MDMA.  I can understand not needing it on a regular day since you'll get it from food, but what about taking before or after MDMA to help recovery?

People take fish and flax oil, thinking it's good for them. People supplement with glutamate and aspartate, thinking it's good for them and not excitotoxic. People take SSRIs, hoping that a synthetic drug can somehow 'cure' their 'depression'. People take estrogen, thinking it'll attenuate menopause. People use fluoridated toothpaste and drink fluoridated water, thinking it won't damage their teeth, bones, and brain. People take iron, calcium carbonate (ground up sea shells), L-DOPA, and countless other supplements which are nearly always more harmful than beneficial. There is an immense amount of disinformation related to supplements, and one should keep in mind that 100 years ago the fashion was calomel (mercurous chloride) radium suppositories. The more things change, the more they stay the same.

5-HTP is excitatory, anti-metabolic, stress-promoting (growth-hormone, prolactin, and cortisol-releasing) pro-inflammatory, potentially carcinogenic monoamine. It is released from platelets and mast cells in response to injury or stress, promoting the constriction of blood vessels and formation of clots. In light of this, most substances that produce a stress response are 'serotonin reuptake inhibitors' which decrease its intracellular concentration and cause it to be released. Its energy-suppressing properties are associated with a variety of chronic energy-related diseases, as well as hibernation.

One of the primary ways by which drugs like psilocin and LSD can so profoundly expand our consciousness is by antagonizing or decreasing the activity of serotonin, which itself has the opposite properties than those that are typically ascribed to it. Psychedelic drugs do not work merely by increasing the activity of serotonin; generally speaking, they replace it in binding sites on proteins, and exert slightly different electronic effects on the protein, which alters its electronic environment, an effect which can potentially be propagated indefinitely. Serotonin is 'released' because its place has been taken by MDMA, and when it diffuses out of the cell it is prone to being metabolized. It may interact with nearby cells, but the characteristic effects of psychedelics  are due to their specific electronic effects, not just the endogenous monoamines which they displace. Serotonin's subjective effects include tropor, helplessness, tranquilization, migraine, and apathy. SSRIs drastically increase the risk of suicide in people who take them, probably for this reason.

Most people's diets contain high levels of tryptophan as well, from muscle meat, fish, dairy, soy, and some vegetables. During infancy and childhood it promotes growth, but during adulthood it is potentially carcinogenic and inhibits differentiation. So supplementing with 5-HTP in the vast majority of cases is harmful in the long term, although the acute effects can vary widely depending on how it's utilized and how your body compensates for its consumption.

Quote
Tryptamine, what do you think about pre-loading an MDMA trip with an MAOI-B or COX Inhibiter?  I was reading about them here: http://www.mdma.net/kobie/simple.html.

I don't agree with some of what he says; for example, that cells are surrounded by a 'plasma membrane' embedded with 'transporters' and 'channels' (a reductionist model that was conclusively disproven over 50 years ago). That said, what he says about 5-HTP competing with pro-oxidant MDMA metabolites for entry into serotonergic neurons sounds feasible, although 5-HTP itself is potentially neurotoxic.

Oxidative damage, one of the two major causes of neurotoxicity, can be substantially attenuated by the consumption of antioxidant vitamins and flavonoids, as well as pro-metabolic substances that direct the oxygen towards respiration and away from inappropriate oxidation targets. Things like fish oil flax oil, and iron are highly pro-oxidant since each molecule of DHA and EHA contains 6 double bonds that can be peroxidated in a reaction that may be catalyzed by iron (this is the main form of oxidative damage). Taking these will generally exacerbate oxidative stress and suppress oxidative metabolism, increasing the likelihood of neurotoxicity.
Many herbs and vitamins are themselves COX inhibitors (for example: Vitamin C, Oligomeric Proanthocyanidins, Alpha Lipoic Acid, Sulbutiamine (if thiamine is deficient), TMG, Pyridoxal (B6),  Naicin (B3), Ginkgo, Rhodiola, Bacopa, Holy Basil, and countless others). MindFood contains all of these; ThinkDeep and ChillPill contain many of them. I would not recommend taking a pharmaceutical drug specifically to inhibit COX; no metabolic process exists in a vacuum, and targeting that specific enzyme with a potent, specific drug will invariably cause imbalances elsewhere. If you really want to go that route, perhaps you could try white willow bark extract, which was the natural inspiration for the less effective and more toxic drug Aspirin.

Quote
And are SRIs on the comedown neuroprotective?  I've never tried this before either.  I usually take a 5HTP and Melatonin.  I'm gonna try taking your chill pills on my next MDMA comedown.

Possibly; however I would not recommend anyone take pharmaceutical SSRIs, ever. Either way, preventing oxidative damage is far more important and non-invasive, and may be at odds with the effects of the SSRIs, which are not necessarily anything more than patented toxins.
My ChillPills contain neither 5-HTP nor melatonin, although the latter may be beneficial to take from time to time.

Bottom line: stop taking pro-oxidant, anti-metabolic substances (iron, PUFA oils (fish, flax, soy, sunflower), 5-HTP/serotonin, amphetamines, glutamate/aspartate), start taking anti-oxidant, pro-metabolic substances (the ones I listed earlier, as well as coconut oil to replace the aforementioned polyunsaturated fat oils), and you can generally prevent neurotoxicity without pushing your metabolism unsustainably in one direction. Metabolism is far more interconnected and fundamental than the membrane/receptor/pump/channel/transporter model implies.

That was a pretty long post. Hopefully a lot of people read it.
Very insightful read, I just bought a jar of fish oil tablets last week because everyone swears by it but I realized today that it's making my skin worse not better. I take 500mg of L-Tryptophan everyday, would you recommend I stop taking them completely or simply lower my dose? My diet is a horrible one and I'm working on fixing that but for now I really do feel like it keeps my mood stable, thanks in advance Trypt and thanks for taking the time to educate us because all "health" companies want to do is sell you products and not educate you on them.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on July 04, 2012, 09:41 pm
Wait, so now 5HTP is bad for you?  That has to be the #1 supplement people take before/after MDMA.  I can understand not needing it on a regular day since you'll get it from food, but what about taking before or after MDMA to help recovery?

People take fish and flax oil, thinking it's good for them. People supplement with glutamate and aspartate, thinking it's good for them and not excitotoxic. People take SSRIs, hoping that a synthetic drug can somehow 'cure' their 'depression'. People take estrogen, thinking it'll attenuate menopause. People use fluoridated toothpaste and drink fluoridated water, thinking it won't damage their teeth, bones, and brain. People take iron, calcium carbonate (ground up sea shells), L-DOPA, and countless other supplements which are nearly always more harmful than beneficial. There is an immense amount of disinformation related to supplements, and one should keep in mind that 100 years ago the fashion was calomel (mercurous chloride) radium suppositories. The more things change, the more they stay the same.

5-HTP is excitatory, anti-metabolic, stress-promoting (growth-hormone, prolactin, and cortisol-releasing) pro-inflammatory, potentially carcinogenic monoamine. It is released from platelets and mast cells in response to injury or stress, promoting the constriction of blood vessels and formation of clots. In light of this, most substances that produce a stress response are 'serotonin reuptake inhibitors' which decrease its intracellular concentration and cause it to be released. Its energy-suppressing properties are associated with a variety of chronic energy-related diseases, as well as hibernation.

One of the primary ways by which drugs like psilocin and LSD can so profoundly expand our consciousness is by antagonizing or decreasing the activity of serotonin, which itself has the opposite properties than those that are typically ascribed to it. Psychedelic drugs do not work merely by increasing the activity of serotonin; generally speaking, they replace it in binding sites on proteins, and exert slightly different electronic effects on the protein, which alters its electronic environment, an effect which can potentially be propagated indefinitely. Serotonin is 'released' because its place has been taken by MDMA, and when it diffuses out of the cell it is prone to being metabolized. It may interact with nearby cells, but the characteristic effects of psychedelics  are due to their specific electronic effects, not just the endogenous monoamines which they displace. Serotonin's subjective effects include tropor, helplessness, tranquilization, migraine, and apathy. SSRIs drastically increase the risk of suicide in people who take them, probably for this reason.

Most people's diets contain high levels of tryptophan as well, from muscle meat, fish, dairy, soy, and some vegetables. During infancy and childhood it promotes growth, but during adulthood it is potentially carcinogenic and inhibits differentiation. So supplementing with 5-HTP in the vast majority of cases is harmful in the long term, although the acute effects can vary widely depending on how it's utilized and how your body compensates for its consumption.

Quote
Tryptamine, what do you think about pre-loading an MDMA trip with an MAOI-B or COX Inhibiter?  I was reading about them here: http://www.mdma.net/kobie/simple.html.

I don't agree with some of what he says; for example, that cells are surrounded by a 'plasma membrane' embedded with 'transporters' and 'channels' (a reductionist model that was conclusively disproven over 50 years ago). That said, what he says about 5-HTP competing with pro-oxidant MDMA metabolites for entry into serotonergic neurons sounds feasible, although 5-HTP itself is potentially neurotoxic.

Oxidative damage, one of the two major causes of neurotoxicity, can be substantially attenuated by the consumption of antioxidant vitamins and flavonoids, as well as pro-metabolic substances that direct the oxygen towards respiration and away from inappropriate oxidation targets. Things like fish oil flax oil, and iron are highly pro-oxidant since each molecule of DHA and EHA contains 6 double bonds that can be peroxidated in a reaction that may be catalyzed by iron (this is the main form of oxidative damage). Taking these will generally exacerbate oxidative stress and suppress oxidative metabolism, increasing the likelihood of neurotoxicity.
Many herbs and vitamins are themselves COX inhibitors (for example: Vitamin C, Oligomeric Proanthocyanidins, Alpha Lipoic Acid, Sulbutiamine (if thiamine is deficient), TMG, Pyridoxal (B6),  Naicin (B3), Ginkgo, Rhodiola, Bacopa, Holy Basil, and countless others). MindFood contains all of these; ThinkDeep and ChillPill contain many of them. I would not recommend taking a pharmaceutical drug specifically to inhibit COX; no metabolic process exists in a vacuum, and targeting that specific enzyme with a potent, specific drug will invariably cause imbalances elsewhere. If you really want to go that route, perhaps you could try white willow bark extract, which was the natural inspiration for the less effective and more toxic drug Aspirin.

Quote
And are SRIs on the comedown neuroprotective?  I've never tried this before either.  I usually take a 5HTP and Melatonin.  I'm gonna try taking your chill pills on my next MDMA comedown.

Possibly; however I would not recommend anyone take pharmaceutical SSRIs, ever. Either way, preventing oxidative damage is far more important and non-invasive, and may be at odds with the effects of the SSRIs, which are not necessarily anything more than patented toxins.
My ChillPills contain neither 5-HTP nor melatonin, although the latter may be beneficial to take from time to time.

Bottom line: stop taking pro-oxidant, anti-metabolic substances (iron, PUFA oils (fish, flax, soy, sunflower), 5-HTP/serotonin, amphetamines, glutamate/aspartate), start taking anti-oxidant, pro-metabolic substances (the ones I listed earlier, as well as coconut oil to replace the aforementioned polyunsaturated fat oils), and you can generally prevent neurotoxicity without pushing your metabolism unsustainably in one direction. Metabolism is far more interconnected and fundamental than the membrane/receptor/pump/channel/transporter model implies.

That was a pretty long post. Hopefully a lot of people read it.
Very insightful read, I just bought a jar of fish oil tablets last week because everyone swears by it but I realized today that it's making my skin worse not better. I take 500mg of L-Tryptophan everyday, would you recommend I stop taking them completely or simply lower my dose? My diet is a horrible one and I'm working on fixing that but for now I really do feel like it keeps my mood stable, thanks in advance Trypt and thanks for taking the time to educate us because all "health" companies want to do is sell you products and not educate you on them.

I'd recommend against taking the Tryptophan, if you feel that it's affecting you I'd taper it off but it'd probably be alright just to stop. It may keep your mood stable, but it does so by suppressing your brain's metabolism. The analogy I like to use is of a temporary chemical lobotomy.
Instead of fish oil you should take coconut oil, it's almost pure saturated fat and is very pro-metabolic and anti-oxidant.

Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: p34r on July 09, 2012, 02:22 am
Any opinion on the glycine in the TMG as a NMDA co-agonist with glutamate?
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on July 09, 2012, 05:17 am
In-vitro studies have found that glycine can exacerbate glutamatergic (or NMDA-induced) NMDAR-mediated excitotoxicity in hippocampus and retina. On the other hand, glycine has been shown to attenuate damage to cortex caused by experimentally-induced ischemia in rats, and in humans improves recovery after ischemic stroke (decreasing levels of GLU and ASP, increasing levels of GABA, and inhibiting lipid peroxidation).
I don't think the excitotoxicity studies are physiologically relevant; the concentration of glycine in 'synaptic clefts' is many orders of magnitude lower than in the surrounding areas, due to uptake by proteins, and the studies that found excitotoxicity had used a concentration of glycine several orders of magnitude higher than physiological concentration, applied for several minutes.
I include TMG (as well as Magnesium Glycinate in the new version of ChillPill) because of glycine's general physiological effects as an anti-excitatory, anti-stress (anti-serotonin), anti-toxic, anti-inflammatory, pro-cognitive agent. Glycine has been found to improve several aspects of cognitive function, especially memory; this may be related to 'NMDA receptors' to some extent, but I don't think it matters either way. Individual 'receptors' are only relevant if you're designing a drug or writing a grant application.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: poolsclosed on July 09, 2012, 02:56 pm
In-vitro studies have found that glycine can exacerbate glutamatergic (or NMDA-induced) NMDAR-mediated excitotoxicity in hippocampus and retina. On the other hand, glycine has been shown to attenuate damage to cortex caused by experimentally-induced ischemia in rats, and in humans improves recovery after ischemic stroke (decreasing levels of GLU and ASP, increasing levels of GABA, and inhibiting lipid peroxidation).
I don't think the excitotoxicity studies are physiologically relevant; the concentration of glycine in 'synaptic clefts' is many orders of magnitude lower than in the surrounding areas, due to uptake by proteins, and the studies that found excitotoxicity had used a concentration of glycine several orders of magnitude higher than physiological concentration, applied for several minutes.
I include TMG (as well as Magnesium Glycinate in the new version of ChillPill) because of glycine's general physiological effects as an anti-excitatory, anti-stress (anti-serotonin), anti-toxic, anti-inflammatory, pro-cognitive agent. Glycine has been found to improve several aspects of cognitive function, especially memory; this may be related to 'NMDA receptors' to some extent, but I don't think it matters either way. Individual 'receptors' are only relevant if you're designing a drug or writing a grant application.
Hearing this, how do your supplements affect dissociative tolerance and effects? I've come to have an uncomfortably high MXE tolerance. (I know, I know, taking RCs is bad for you...)
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on July 09, 2012, 04:32 pm
In-vitro studies have found that glycine can exacerbate glutamatergic (or NMDA-induced) NMDAR-mediated excitotoxicity in hippocampus and retina. On the other hand, glycine has been shown to attenuate damage to cortex caused by experimentally-induced ischemia in rats, and in humans improves recovery after ischemic stroke (decreasing levels of GLU and ASP, increasing levels of GABA, and inhibiting lipid peroxidation).
I don't think the excitotoxicity studies are physiologically relevant; the concentration of glycine in 'synaptic clefts' is many orders of magnitude lower than in the surrounding areas, due to uptake by proteins, and the studies that found excitotoxicity had used a concentration of glycine several orders of magnitude higher than physiological concentration, applied for several minutes.
I include TMG (as well as Magnesium Glycinate in the new version of ChillPill) because of glycine's general physiological effects as an anti-excitatory, anti-stress (anti-serotonin), anti-toxic, anti-inflammatory, pro-cognitive agent. Glycine has been found to improve several aspects of cognitive function, especially memory; this may be related to 'NMDA receptors' to some extent, but I don't think it matters either way. Individual 'receptors' are only relevant if you're designing a drug or writing a grant application.
Hearing this, how do your supplements affect dissociative tolerance and effects? I've come to have an uncomfortably high MXE tolerance. (I know, I know, taking RCs is bad for you...)

I have not heard reports about that, and would rather not venture a guess on such things. If you ever do take them concurrently, I'd be interested to hear your experience.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: collarbones on July 11, 2012, 03:02 pm
Man this is a great thread, Trypt dropping knowledge everywhere. I just wanted to say thanks and that I really appreciate it. Keep up the great work sir.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on July 14, 2012, 04:01 am
New MindFood 3.1 out tomorrow, they no longer contain N-Acetyl Tyrosine, but they now have over twice as much picamilon and slightly more TMG!
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: awakened350 on July 14, 2012, 04:51 am
Wait, so now 5HTP is bad for you?  That has to be the #1 supplement people take before/after MDMA.  I can understand not needing it on a regular day since you'll get it from food, but what about taking before or after MDMA to help recovery?

People take fish and flax oil, thinking it's good for them. People supplement with glutamate and aspartate, thinking it's good for them and not excitotoxic. People take SSRIs, hoping that a synthetic drug can somehow 'cure' their 'depression'. People take estrogen, thinking it'll attenuate menopause. People use fluoridated toothpaste and drink fluoridated water, thinking it won't damage their teeth, bones, and brain. People take iron, calcium carbonate (ground up sea shells), L-DOPA, and countless other supplements which are nearly always more harmful than beneficial. There is an immense amount of disinformation related to supplements, and one should keep in mind that 100 years ago the fashion was calomel (mercurous chloride) radium suppositories. The more things change, the more they stay the same.

5-HTP is excitatory, anti-metabolic, stress-promoting (growth-hormone, prolactin, and cortisol-releasing) pro-inflammatory, potentially carcinogenic monoamine. It is released from platelets and mast cells in response to injury or stress, promoting the constriction of blood vessels and formation of clots. In light of this, most substances that produce a stress response are 'serotonin reuptake inhibitors' which decrease its intracellular concentration and cause it to be released. Its energy-suppressing properties are associated with a variety of chronic energy-related diseases, as well as hibernation.

One of the primary ways by which drugs like psilocin and LSD can so profoundly expand our consciousness is by antagonizing or decreasing the activity of serotonin, which itself has the opposite properties than those that are typically ascribed to it. Psychedelic drugs do not work merely by increasing the activity of serotonin; generally speaking, they replace it in binding sites on proteins, and exert slightly different electronic effects on the protein, which alters its electronic environment, an effect which can potentially be propagated indefinitely. Serotonin is 'released' because its place has been taken by MDMA, and when it diffuses out of the cell it is prone to being metabolized. It may interact with nearby cells, but the characteristic effects of psychedelics  are due to their specific electronic effects, not just the endogenous monoamines which they displace. Serotonin's subjective effects include tropor, helplessness, tranquilization, migraine, and apathy. SSRIs drastically increase the risk of suicide in people who take them, probably for this reason.

Most people's diets contain high levels of tryptophan as well, from muscle meat, fish, dairy, soy, and some vegetables. During infancy and childhood it promotes growth, but during adulthood it is potentially carcinogenic and inhibits differentiation. So supplementing with 5-HTP in the vast majority of cases is harmful in the long term, although the acute effects can vary widely depending on how it's utilized and how your body compensates for its consumption.

Quote
Tryptamine, what do you think about pre-loading an MDMA trip with an MAOI-B or COX Inhibiter?  I was reading about them here: http://www.mdma.net/kobie/simple.html.

I don't agree with some of what he says; for example, that cells are surrounded by a 'plasma membrane' embedded with 'transporters' and 'channels' (a reductionist model that was conclusively disproven over 50 years ago). That said, what he says about 5-HTP competing with pro-oxidant MDMA metabolites for entry into serotonergic neurons sounds feasible, although 5-HTP itself is potentially neurotoxic.

Oxidative damage, one of the two major causes of neurotoxicity, can be substantially attenuated by the consumption of antioxidant vitamins and flavonoids, as well as pro-metabolic substances that direct the oxygen towards respiration and away from inappropriate oxidation targets. Things like fish oil flax oil, and iron are highly pro-oxidant since each molecule of DHA and EHA contains 6 double bonds that can be peroxidated in a reaction that may be catalyzed by iron (this is the main form of oxidative damage). Taking these will generally exacerbate oxidative stress and suppress oxidative metabolism, increasing the likelihood of neurotoxicity.
Many herbs and vitamins are themselves COX inhibitors (for example: Vitamin C, Oligomeric Proanthocyanidins, Alpha Lipoic Acid, Sulbutiamine (if thiamine is deficient), TMG, Pyridoxal (B6),  Naicin (B3), Ginkgo, Rhodiola, Bacopa, Holy Basil, and countless others). MindFood contains all of these; ThinkDeep and ChillPill contain many of them. I would not recommend taking a pharmaceutical drug specifically to inhibit COX; no metabolic process exists in a vacuum, and targeting that specific enzyme with a potent, specific drug will invariably cause imbalances elsewhere. If you really want to go that route, perhaps you could try white willow bark extract, which was the natural inspiration for the less effective and more toxic drug Aspirin.

Quote
And are SRIs on the comedown neuroprotective?  I've never tried this before either.  I usually take a 5HTP and Melatonin.  I'm gonna try taking your chill pills on my next MDMA comedown.

Possibly; however I would not recommend anyone take pharmaceutical SSRIs, ever. Either way, preventing oxidative damage is far more important and non-invasive, and may be at odds with the effects of the SSRIs, which are not necessarily anything more than patented toxins.
My ChillPills contain neither 5-HTP nor melatonin, although the latter may be beneficial to take from time to time.

Bottom line: stop taking pro-oxidant, anti-metabolic substances (iron, PUFA oils (fish, flax, soy, sunflower), 5-HTP/serotonin, amphetamines, glutamate/aspartate), start taking anti-oxidant, pro-metabolic substances (the ones I listed earlier, as well as coconut oil to replace the aforementioned polyunsaturated fat oils), and you can generally prevent neurotoxicity without pushing your metabolism unsustainably in one direction. Metabolism is far more interconnected and fundamental than the membrane/receptor/pump/channel/transporter model implies.

That was a pretty long post. Hopefully a lot of people read it.

Read it and greatly appreciated it! I find brain chemistry absolutely fascinating. I'd love to learn more but the learning curve seems quite steep with infinite contradictory information. Any advice on how to get a good foundation and quality info?
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on July 14, 2012, 05:07 am
Read it and greatly appreciated it! I find brain chemistry absolutely fascinating. I'd love to learn more but the learning curve seems quite steep with infinite contradictory information. Any advice on how to get a good foundation and quality info?
Glad you asked.

This is a good place to start, although it is rather long and rigorous (nothing compared to his books):

http://www.physiologicalchemistryandphysics.com/pdf/PCP39-2_ling.pdf

A shorter, more informal paper (still pretty heady)

http://gilbertling.org/pdf/PCP41_ling.pdf

If that's still too much, start with this powerpoint summary of the 'new paradigm':

http://gilbertling.org/Gilbert%20Ling%20Lecture%2021.ppt

Gilbert Ling is a biophysicist who has been doing biological research for nearly 70 years. He invented the microelectrode, and his theory of the cell was the basis for Magnetic Resonance Imaging. He has refuted the popular image of cells (as aqueous solutions surrounded by phospholipid bilayer membranes filled with pumps and channels) at great length, but his research has been ignored by those who write grants and textbooks, for reasons that become apparent once you read his work. Popular opinion aside, if you want to understand life on the most fundamental level, you need to become familiar with his work (and the work of his predecessors).
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: awakened350 on July 14, 2012, 06:16 am
Thanks! Bookmarked them all and will start digging in.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Ahoyhoy on July 14, 2012, 10:35 am

Interested in the mind food - is there empirical evidence for effectiveness of these supplements? Can you point me in the direction of the research? I'm really interested in all this stuff...

I take supplements already to counter the negative effects of rolling on E.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Bob Arctor on July 14, 2012, 10:49 am
Hey, Tryptamine, you seem knowledgeable in this area. How long and what dosages of piracetam should be taken for noticeable cognitive improvement?
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on July 14, 2012, 05:25 pm

Interested in the mind food - is there empirical evidence for effectiveness of these supplements? Can you point me in the direction of the research? I'm really interested in all this stuff...

I take supplements already to counter the negative effects of rolling on E.

There is a ton of empirical evidence (as well as rational justifications) for each of the ingredients I use in my supplement, as well as some combinations. I have it all collected in a giant text file which I will format and post here one of these days.
As for empirical research about my specific blends of supplements, there isn't any, apart from the fact that they work (check my review thread and/or my item listings).

Hey, Tryptamine, you seem knowledgeable in this area. How long and what dosages of piracetam should be taken for noticeable cognitive improvement?

I include 150mg of piracetam in each ThinkDeep, which I believe synergizes with the other ingredients. On its own, I'd recommend 1gram+ per day; you should feel it the first time you take it, but the physiological effects will be cumulative. I took about 5 grams a day for a year a few years back, did me good.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Caparino on July 15, 2012, 01:49 am

Interested in the mind food - is there empirical evidence for effectiveness of these supplements? Can you point me in the direction of the research? I'm really interested in all this stuff...

I take supplements already to counter the negative effects of rolling on E.

There is a ton of empirical evidence (as well as rational justifications) for each of the ingredients I use in my supplement, as well as some combinations. I have it all collected in a giant text file which I will format and post here one of these days.
As for empirical research about my specific blends of supplements, there isn't any, apart from the fact that they work (check my review thread and/or my item listings).

Hey, Tryptamine, you seem knowledgeable in this area. How long and what dosages of piracetam should be taken for noticeable cognitive improvement?

I include 150mg of piracetam in each ThinkDeep, which I believe synergizes with the other ingredients. On its own, I'd recommend 1gram+ per day; you should feel it the first time you take it, but the physiological effects will be cumulative. I took about 5 grams a day for a year a few years back, did me good.

Is piracetam available OTC? If not, what the most cost-effective way to get my hands on some?
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: l1llykins on July 15, 2012, 03:04 am
You wont find them in stores but you can find them online. I got mine from Amazon.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Caparino on July 15, 2012, 07:30 am
You wont find them in stores but you can find them online. I got mine from Amazon.

Wow, thanks l1lly! Found a cheap source for them.

One last question Tryptamine. I'm looking to normalize my cognitive and overall neurological function after about 1.5 years of binge drinking, adderall usage, and psychedelic experimentation; in addition to your mindfood capsules and piracetam, what supplements do you recommend? I'm sure the answer will help not only me, but also many others!

-Cap
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: numbering on July 15, 2012, 06:43 pm
Hello, I still don't get the point of using the ThinkDeep pills. Do they prevent me from having a hangover and *-toxic effects of amphetamines for example or do they have another drug like effect also? Or do they even reduce hangovers?
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on July 15, 2012, 10:50 pm
You wont find them in stores but you can find them online. I got mine from Amazon.

Wow, thanks l1lly! Found a cheap source for them.

One last question Tryptamine. I'm looking to normalize my cognitive and overall neurological function after about 1.5 years of binge drinking, adderall usage, and psychedelic experimentation; in addition to your mindfood capsules and piracetam, what supplements do you recommend? I'm sure the answer will help not only me, but also many others!

-Cap

Check my recent posts on the forum. In short, vitamin C, flavonoids, vitamin D, vitamin K, magnesium, chlorella/spirulina, coconut oil, fruit. Avoid fish and grains.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Caparino on July 15, 2012, 11:33 pm
You wont find them in stores but you can find them online. I got mine from Amazon.

Wow, thanks l1lly! Found a cheap source for them.

One last question Tryptamine. I'm looking to normalize my cognitive and overall neurological function after about 1.5 years of binge drinking, adderall usage, and psychedelic experimentation; in addition to your mindfood capsules and piracetam, what supplements do you recommend? I'm sure the answer will help not only me, but also many others!

-Cap

Check my recent posts on the forum. In short, vitamin C, flavonoids, vitamin D, vitamin K, magnesium, chlorella/spirulina, coconut oil, fruit. Avoid fish and grains.

Wow I'm forever grateful to you man :)
Vitamin K1 or K2? or does it even matter?
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on July 15, 2012, 11:44 pm
K2 is probably better.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Caparino on July 16, 2012, 12:09 am
How come?

Edit: +1 for answering all these questions.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on July 16, 2012, 01:26 am
K2 is the endogenous form, synthesized in the large intestine. K1 is the form found in plants, which our intestines partially convert to K2. Most of the research on vitamin K is done on vitamin K2.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on July 16, 2012, 05:59 am
Well, it took 3.5 hours of intense manual labor and didn't go as smoothly I would've liked, but I now have  ~600 new MindFood capsules for sale. I'm nearly out of Picamilon, though, so ChillPills may take another day or two.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Briggs on July 16, 2012, 08:03 am
Are you planning to have a sampler pack for all 3 types in the near future? I have enough coin to do a 5 capsule order, however I am having a lot of trouble making a choice on which I should try out first! Leaning more towards Mind Food or ThinkDeep for round 1.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: collarbones on July 16, 2012, 01:22 pm
Hey Trypt, any thoughts on piracetam vs aniracetam vs oxiracetam? Which do you prefer/avoid and why?
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: blowdrobro on July 16, 2012, 05:26 pm
Hey, Tryp. I'm really interested in your product. I use to take a lot of noots but I didn't notice any effects ( still got a tub of pricatam in my closet lol). Would you're product be OK to take with  SNRI's, and benzo's--apart from cannabis this is the only drugs I use and they're prescribed. Also a major concern for me: are your ingredents from US FDA approved labs and do you have any purity tests? I'm a law student and I have to memorize a lot of information. I think I'd like to try the Mindfood.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on July 16, 2012, 06:39 pm
Are you planning to have a sampler pack for all 3 types in the near future? I have enough coin to do a 5 capsule order, however I am having a lot of trouble making a choice on which I should try out first! Leaning more towards Mind Food or ThinkDeep for round 1.

Yes, I'll have it up within a couple of days, once I make more ChillPills.

Hey Trypt, any thoughts on piracetam vs aniracetam vs oxiracetam? Which do you prefer/avoid and why?

Piracetam's the best studied, aniracetam is second, and oxiracetam is probably third . There's a lot of research about oxiracetam (and pir, and ani) on mice and rats, where it's found to protect against cognitive dysfunction induced by certain toxins, and generally to increase arousal. Studies on 'demented' humans have shown mixed results, with some showing benefit and some not at all, but such studies have very limited value anyway since what they're measuring is changes in clinical symptoms or answers to a questionnaire. Aniracetam has been used to treat vascular dementia, hypoxia, and ischemia, as is piracetam. Its safety, and that of piracetam, are well established. Oxiracetam is probably also safe, although I personally haven't done as much research on it. If it checks out I may include it in a future ThinkDeep. I'd stick to those three, though; the other racetams are less well-studied and some of them may produce adverse effects.

Hey, Tryp. I'm really interested in your product. I use to take a lot of noots but I didn't notice any effects ( still got a tub of pricatam in my closet lol). Would you're product be OK to take with  SNRI's, and benzo's--apart from cannabis this is the only drugs I use and they're prescribed. Also a major concern for me: are your ingredents from US FDA approved labs and do you have any purity tests? I'm a law student and I have to memorize a lot of information. I think I'd like to try the Mindfood.

Those drugs shouldn't be an issue, although do keep in mind that they're probably not substances that a human should be consuming with any regularity, regardless of what the FDA may decree, and what your psychiatrist may believe.
As for FDA approved labs, I can't say that I've confirmed that all of my suppliers are GMP. I use a lot of rare and expensive ingredients, for which I often have very few sources. All of my herbal extracts come with certificates of analysis, as do most of my nutraceuticals. My capsules themselves are, of course, not FDA approved.
That said, the FDA is little more than a racket that exists to promulgate disinformation about biology to support the interests and prejudices of the pharmaceutical industry and eliminate competition, a way for delinquent individuals to advance their 'political careers' by granting special favors, and bestowing a false sense of safety and authority upon drugs that kill hundreds of thousands of people each year. They spend most of their energy going after people like myself, who use natural and orthomolecular (as opposed to synthetic and patented) substances to improve people's health, which is the main reason why I'm 'underground' on the 'Road. If you're a law student and you've found your way to the 'Road, I imagine you're probably at least vaguely aware of this. Or maybe not.

Here's a quote I like:

"There was open drunkenness by several employees which went on for months ... crippled by what some people called the worst personnel in government. There was intimidation internally by people . . . People, I'm talking about division directors and their staff, would engage in a kind of behavior that invited . . . insubordination - people tittering in comers, throwing spitballs; I am describing physicians, people who would . . . slouch down in a chair, not respond to questions, moan and groan with sweeping gestures, a kind of behavior I have not seen in any other institution as a grown man . . . Prior to 1974, not one scientific officer in our place knew his work assignments, nor did any manager know the work assignment of the people under him."

-Dr. J. Richard Crout, former director of FDA Bureau of Drugs, congressional testimony April 19 1976
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: l1llykins on July 16, 2012, 08:20 pm
Consider that the FDA is the reason you can't find Piracetam in stores :o.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Caparino on July 16, 2012, 09:48 pm
Consider that the FDA is the reason you can't find Piracetam in stores :o.

Out of all things the FDA causes both directly and indirectly, you mention Piracetam's absence in stores?
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: l1llykins on July 16, 2012, 10:09 pm
Consider that the FDA is the reason you can't find Piracetam in stores :o.

Out of all things the FDA causes both directly and indirectly, you mention Piracetam's absence in stores?

... that was in response to blowdrobro's question about FDA approval ingredients in the same post he mentions having taken piracetam in the past.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Caparino on July 16, 2012, 10:13 pm
Consider that the FDA is the reason you can't find Piracetam in stores :o.

Out of all things the FDA causes both directly and indirectly, you mention Piracetam's absence in stores?

... that was in response to blowdrobro's question about FDA approval ingredients in the same post he mentions having taken piracetam in the past.

I was just sayin  :D
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: blowdrobro on July 17, 2012, 01:52 am
Sorry for the confusion. I forgot the specific term, but Tryp asnwered my question anyway lol. I was wondering if the labs he bought from were GMP certified and they are. That was the real concern among people I talked with about noots.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on July 18, 2012, 04:27 am
I may be leaving in 2 days, so any orders placed after tomorrow morning may take a few more days to ship.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Eatshitanddie69 on July 18, 2012, 07:58 am
Yummy!
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Caparino on July 24, 2012, 02:12 am
Hey Trypt, a while back you mentioned that you took piracetam daily for a year and it did you some good; why did you stop?
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on July 24, 2012, 08:06 pm
Hey Trypt, a while back you mentioned that you took piracetam daily for a year and it did you some good; why did you stop?

I still take it, I just used to take much larger amounts because I would dissolve it with ALCAR in water and take shots of it. The taste was unpleasant though, and now I just fill capsules with it.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: msft1 on July 25, 2012, 12:59 pm
Hey, Tryp. Long time lurker here. Couple of questions:

First, I've I've been wanting to buy your stuff for some time and now I've got some coins laying around. However, none of your products are listed. Are you planning on re-stocking soon?


Second, I've read this entire thread and definitely want to try acetams. I've found the following product on Amazon which seems to be a convenient combination:

http://www.amazon.com/gp/product/B008N6JTH8
Build Your Own Blend Supplements
Nootropic Stack 90 Day Supply Bulk Powder
Directions
Nootropic stack can be taken once in the morning, and once in the early afternoon in the following dosages: {250-750mg Sulbutiamine} {100-200mg Caffeine Anhydrous} {500mg-1g Choline CDP} {250mg Pramiracetam (morning only)} {750mg - 1.5g Aniracetam (morning only)} {20mg Noopept (afternoon only)} {750mg - 1.5g Oxiracetam (afternoon only)}

I wouldn't mind dropping ~$300 on a 90-day supply but I'd want your opinion on it first.

Lastly, would taking acetams and/or blends like this one interfere and/or compliment your products? Is there even a point in taking this blend above, or would it be wiser to just try your products first (ThinkDeep and ChillPill is what I'm after).

Note that at the moment I'm not taking anything and I'm a casual DMT, LSD, and weed user.

Thanks in advance for your time.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on July 25, 2012, 02:21 pm
Just got back from 'vacation', I'll relist once SR is back up. I'll have new ChillPills available by tomorrow.

I would not recommend taking sulbutiamine at anywhere near their 'recommended' dosage. When used at extremely high doses as a 'nootropic' sulbutiamine can have deleterious and pseudo-addictive effects; I use a much smaller amount in MindFood and ThinkDeep as an enhanced form of vitamin B1. The RDA of Thiamine (B1) is 1mg per day; this is irresponsibly low, but I don't think people should be taking more than a few dozen mg of it per day, if that.
The caffeine dosage is also very high (at least, for me) as is the CDP-choline dosage. The racetam dosages are fine, although you should research them before taking them, since they are after all synthetic chemicals that you're taking in enormous amounts. Piracetam, aniracetam, and oxiracetam are the best studied and are probably completely safe; on the other hand, not everything that's called a 'racetam' has that property, just as not everything that is called a 'cannabinoid' is as safe as cannabis.

Racetams (pi, ani, possibly oxi) would be a good supplement to my products, since they can be taken at large doses. More CDP choline is probably unnecessary, but you could try. NooPept could also be taken at a larger dose; the main reason I use small doses in my products is that it's extremely expensive, although I've recently found a much cheaper source that might change that.
 
Bottom line, I'd recommend you buy the ingredients that you need individually. Caffeine is superfluous, and if you're prepared to take 100mg to 200mg then you're probably already a heavy user and don't need more.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: poolsclosed on July 26, 2012, 12:13 am
I'd just like to chime in and say that the amount of caffeine in there is ridiculous. Caffeine isn't therapeutic at such high doses. A large cup of coffee is a freaking overdose. Caffeine, much like nicotene, builds a tolerance and a dependance very quickly. Unlike nicotene it has a large variety of health benefits, but only at very low doses. I tend to just avoid it altogether... I used to consume several grams a day and sleep right through it. 60 ounces of Pepsi Max just to lull myself to sleep... you should follow Trypt's advice and if you are going to supplement with caffeine I would personally say keep it between 25-50mg a day. Better yet, don't put it in your supplements... have a cup of green tea in the morning!
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: msft1 on July 26, 2012, 03:11 am
Thanks, Tryptamine and poolsclosed. I would personally stay away from caffeine myself and I don't really get why it's even in the mix when it can be obtained naturally via tea or coffee.

I'll be sure to snatch up some of your product with the new SR interface. Too bad you don't keep your SR user page link in the signature so I have no easy way of finding you... Gotta find your thread first and go from there :)
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on July 26, 2012, 05:38 pm
The globe beneath my avatar is a link to my SR profile. I could put it in my signature, but then I'd have no room for the William Blake aphorism.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: stamkos on July 26, 2012, 10:26 pm
Does any of your meds work for stroke victims to kick start their brain again like Apomorfin and zolpidem?


Thanks
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on July 26, 2012, 11:07 pm
Yes, nearly all of the ingredients in MindFood and ThinkDeep have been individually found to aid recovery after stroke.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: dannypricefixer on July 27, 2012, 03:44 am
This is worth looking into.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on July 27, 2012, 06:15 pm
This is worth looking into.

I'll post  scientific references (with summaries) in a couple weeks, so that everyone can understand the role of each ingredient.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: sobriquet093 on July 27, 2012, 06:38 pm
mwahahha he is just husslin to get you all to buy his stuff this is  goofy.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on July 27, 2012, 09:14 pm
mwahahha he is just husslin to get you all to buy his stuff this is  goofy.

You're goofy.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on July 28, 2012, 03:11 am
New ChillPills finally in stock (version 3.2)! Now with more Picamilon, Damiana, and Magnesium Glycinate (and slightly less theanine, OPCs, and TMG)!

http://silkroadvb5piz3r.onion/index.php/silkroad/item/f4fee76ba1
http://silkroadvb5piz3r.onion/index.php/silkroad/item/4dc5679867
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: msft1 on August 01, 2012, 05:31 pm
I noticed MindFood listing http://silkroadvb5piz3r.onion/index.php/silkroad/item/e42efbf786 is for 24 count but the price seems too low to be right. Is this listing correct?
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on August 01, 2012, 07:04 pm
No, that listing is for 5 MindFood, thanks for pointing that out. Hopefully nobody bought it who expected 24.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: l1llykins on August 05, 2012, 04:50 am
I preloaded with the new mind food yesterday one hour before taking some MDMA and MDA. I definitely feel the difference between the 2.x and the current batch. The last batch I would feel a little tired the next day and could never seem to avoid the worn muscle feeling and figured it was just a product of me staying up so late and being my age, lol. But today I woke up energized with an amazing afterglow and felt that way for most of the day, a vast improvement.

I'm sorry to say the chill pills didn't help me sleep afterward. I took one at 2am and by 2:30 I only felt slightly less wired. So I took a second pill and decided to wait a full hour this time. I was definitely settling down more but my mind wouldn't quiet long enough to fall asleep, was getting pretty vivid CEV's from the MDA and it was keeping my mind too active. So I ended up taking my usual 2g of ghb and had a good 6 hours of sleep.

The chill pills post roll might have contributed to how I was feeling this morning and all day today, will try without the chill pill next time to confirm, probably around October.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: l1llykins on August 07, 2012, 04:45 am
need to backtrack a bit to ask this question:

I'm looking to normalize my cognitive and overall neurological function after about 1.5 years of binge drinking, adderall usage, and psychedelic experimentation; in addition to your mindfood capsules and piracetam, what supplements do you recommend?
In short, vitamin C, flavonoids, vitamin D, vitamin K, magnesium, chlorella/spirulina, coconut oil, fruit. Avoid fish and grains.

I was wondering why Vitamin K is in that list. I know it's good for clotting if a person is particularly deficient.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on August 07, 2012, 05:52 am
need to backtrack a bit to ask this question:

I'm looking to normalize my cognitive and overall neurological function after about 1.5 years of binge drinking, adderall usage, and psychedelic experimentation; in addition to your mindfood capsules and piracetam, what supplements do you recommend?
In short, vitamin C, flavonoids, vitamin D, vitamin K, magnesium, chlorella/spirulina, coconut oil, fruit. Avoid fish and grains.

I was wondering why Vitamin K is in that list. I know it's good for clotting if a person is particularly deficient.

It is required to add CO2 to glutamate residues in certain proteins, giving them an affinity for calcium. It promotes calcium uptake by bones and prevents soft tissue calcification.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: l1llykins on August 07, 2012, 04:22 pm
Ok thanks, am about to partake in a cleanse myself in preparation for a long weekend, hehe :-).
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: msft1 on August 07, 2012, 04:50 pm
Hey Tryptamine, I've already ordered MindFood and ThinkDeep (so far received ThinkDeep and taking) and now would like to order ChillPills as well. You don't have any listings up; any word on when you'll have them up again? Thanks.

I have a friend who has big issues with sleep (due to being diagnosed with schizo) so hopefully the ChillPills will help at least a bit.

I've also ordered the set of vitamins and other supplements you recommend (as well as NooPept) and will be supplementing you stuff with them. Can't wait to turn into a genius mastermind and win a Nobel prize or two ;)
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on August 07, 2012, 05:34 pm
Just came out of vacation mode, listings should be up now.
Title: brain damage
Post by: smashed on August 07, 2012, 05:42 pm
do you have any pills that reverse brain damage?
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on August 07, 2012, 06:04 pm
All of them reverse brain damage. Especially MindFood.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: smashed on August 07, 2012, 06:08 pm
All of them reverse brain damage. Especially MindFood.

so they restore damage to brain receptors or just prevent further damages?
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Tryptamine on August 07, 2012, 06:46 pm
All of them reverse brain damage. Especially MindFood.

so they restore damage to brain receptors or just prevent further damages?

Yes, many of their ingredients have been found to reverse brain damage and aging, and several customers have reported such results from using my supplements.
Title: Re: Protect against brain damage, improve your cognition & sleep more deeply.
Post by: conflict on August 13, 2012, 08:25 pm
Getting the 24 pack mind food bottles back in anytime soon mate ?
Title: Re: The best natural/orthomolecular/nootropic supplements in existence.
Post by: Tryptamine on August 14, 2012, 03:48 pm
Probably in about a week, although it may take longer.
Title: Re: The best natural/orthomolecular/nootropic supplements in existence.
Post by: Joey Terrifying on August 28, 2012, 03:03 am
yo tryp,  you on vacation?  had a bottle of chillpills in my cart but they have vanished....
Title: Re: The best natural/orthomolecular/nootropic supplements in existence.
Post by: nothingmattress on August 29, 2012, 02:56 am
After receiving only half my order and Trypt promising me to send the other half, month later I still have not received it. Communication is pretty slow. Luckily I didn't finalize so I got half of the coins back. If I ever receive what was promised, I'll pay and update feedback.

As far as what I did receive (Think Deep), the product appears legitimate. I emptied a pill into milligram scale and it came out to be about 600 mg. According to list of ingredients on the bottle, each pill should be about.. 600 mg. So, weight matches perfectly.

Image: http://xfq5l5p4g3eyrct7.onion/view.php?image=c56d41da40ecb42abc58e3f63e978047.jpg

Effects: I noticed a gain in brain function. I tend to be better at focusing, problem-solving, and communication. I can't guarantee that it's due to Think Deep alone, since I'm also exercising and taking other supplements recommended by Trypt (namely C, D, K-2, bioflavanoids, magnesium, noopept), and getting plenty of sleep. I do get slight headaches from time to time that started with these supplements, but can't tell what exactly is causing them.

Overall, I believe he has a good product, a bit expensive and delivery could be better, given that it's not a prohibited substance and not crossing any borders.
Title: Re: The best natural/orthomolecular/nootropic supplements in existence.
Post by: poolsclosed on August 31, 2012, 05:53 pm
After receiving only half my order and Trypt promising me to send the other half, month later I still have not received it. Communication is pretty slow. Luckily I didn't finalize so I got half of the coins back. If I ever receive what was promised, I'll pay and update feedback.

As far as what I did receive (Think Deep), the product appears legitimate. I emptied a pill into milligram scale and it came out to be about 600 mg. According to list of ingredients on the bottle, each pill should be about.. 600 mg. So, weight matches perfectly.

Image: http://xfq5l5p4g3eyrct7.onion/view.php?image=c56d41da40ecb42abc58e3f63e978047.jpg

Effects: I noticed a gain in brain function. I tend to be better at focusing, problem-solving, and communication. I can't guarantee that it's due to Think Deep alone, since I'm also exercising and taking other supplements recommended by Trypt (namely C, D, K-2, bioflavanoids, magnesium, noopept), and getting plenty of sleep. I do get slight headaches from time to time that started with these supplements, but can't tell what exactly is causing them.

Overall, I believe he has a good product, a bit expensive and delivery could be better, given that it's not a prohibited substance and not crossing any borders.
I am sad to hear you have had poor communication from him. I received a wrong item in my order and he re-sent the right item 2 days after we settled the matter and it arrived 3 days after that! Free of charge. You should reach out to him again.

And as far as your headaches go, how much noopept are you taking daily? Too much could explain your headache. I think wiki says people take 10-20mg a few times daily, but I would say all things considered some people could find 20+mg a day to be too much.
Title: Re: The best natural/orthomolecular/nootropic supplements in existence.
Post by: Caparino on September 14, 2012, 07:52 am
So I know there aren't any adverse long term effects for the -racetam family and controlled amounts of noopept but isn't our body prone to becoming used to any subtances we intake? A dependency if you will. I'm afraid that if I cycle these substances for long periods of time, I'll have to continue their usage or my mind's dependency on them will make me stupid at the end of my use.

Does that fear/thought make any sense?
Title: Re: Protect and Heal Your Brain
Post by: Tryptamine on January 27, 2013, 02:41 am
I’m back. New and improved MindFood and ChillPill (version 4.0) now on sale - now with a longer shelf-life and glossy, professionally printed labels.
Title: Re: Protect and Repair Your Brain
Post by: tea_drinker on January 30, 2013, 07:51 am
Welcome back!  8)

What do you think about a product called 'lypo spheric vitamin c'? Apparently it can get the same amount of C into your system as an injection.
Title: Re: Protect and Repair Your Brain
Post by: Tryptamine on February 04, 2013, 03:06 am
It’s an interesting concept, and people have apparently reported positive results, but I was unable to find any scientific papers on it (to which I have access). I remember reading online a guide to making it yourself using lecithin.
Title: Re: Protect and Repair Your Brain
Post by: nothingmattress on February 25, 2013, 05:40 am
About lypo spheric vitamin c - my best friend's brother-in-law apparently got cured with "vitamin C injections" from blood cancer. It was progressing and the family decided on vitamin c injections over chemotherapy, and apparently it worked - haven't heard any bad news so far, it's been over a year since he got back to normal.
Title: Re: Protect and Repair Your Brain
Post by: SelfSovereignty on February 25, 2013, 06:05 am
... wait, isn't that a fucking episode of House I saw half of once?!  Give me a break...
Title: Re: Protect and Repair Your Brain
Post by: Tryptamine on February 25, 2013, 07:01 am
About lypo spheric vitamin c - my best friend's brother-in-law apparently got cured with "vitamin C injections" from blood cancer. It was progressing and the family decided on vitamin c injections over chemotherapy, and apparently it worked - haven't heard any bad news so far, it's been over a year since he got back to normal.

Large doses of vitamin C have long been known to alleviate and even cure many types of cancer; since humans can't produce it ourselves, and our diets do not provide us with the 10g or so that we should be consuming every day, virtually everyone alive today can be thought of as suffering from subclinical scurvy, due to impaired collagen synthesis. This promotes tumor metastasis, since the connective tissue is weakened; in addition, ascorbate inactivates the hyaluronidases secreted by tumor cells to dissolve connective tissue.
Title: Re: Protect and Repair Your Brain
Post by: SelfSovereignty on February 25, 2013, 07:41 am
I'm no biologist and I do not claim to have expertise exceeding yours, Tryptamine -- but I just don't buy that.  I just don't buy it.  You're trying to tell me that large doses of ascorbic acid when regularly administered not only stop the growth of a run away, cancerous tumor that's multiplying without checks and balances, but that it also allows your body to destroy it...?  That's just not something I can believe is truly significantly more effective than placebo.
Title: Re: Protect and Repair Your Brain
Post by: Tryptamine on February 25, 2013, 05:22 pm
I'm no biologist and I do not claim to have expertise exceeding yours, Tryptamine -- but I just don't buy that.  I just don't buy it.  You're trying to tell me that large doses of ascorbic acid when regularly administered not only stop the growth of a run away, cancerous tumor that's multiplying without checks and balances, but that it also allows your body to destroy it...?  That's just not something I can believe is truly significantly more effective than placebo.

Not only that, but often times (perhaps most of the time) the reason for its spread is a deficiency in ascorbate. If I told you the same thing about a chemotherapy drug, would you have 'believed' it then? Cancers do not arise because we don't take enough chemotherapy drugs; they rise due to persistent imbalances in our physiology, which although often induced by environmental factor, ultimately relate to the amounts and activities of vitamins and metaboiltes.
Only someone who sees the tumor as an external, as a malicious, foreign, rebellious enemy which must be annihilated by all means necessary, would deny the fact that the tumor is ultimately produced by your own body, by the same structures that normally  function non-cancerously. The reasons toxic, expensive, indiscriminate chemotherapy agents are typically used on cancer patients 1. the physiologist denies the endogenous origin of the tumor (preferring to conceive of it as an enemy), and in the same stroke denies the inherent healing and self-organizing tendency of our body and our cells (which is the basis of my products) and 2. in order to be consistently perscribed by doctors, a drug must be patented, so that the state will enforce the medical monopoly on its use, ensuring huge profits for the drug company and also the doctors that perscribe the drugs. In order to be patented, a drug must be shown to be different from anything known to exist naturally. What drug companies will do is find a plant that has significant anti-cancer activity, isolate one of its components, modify its chemical structure slightly to make it a 'novel creation', and sell that chemical at insane prices as a cancer treatment.
At no point in this process has anyone thought of the well being of the patient. Granted, many doctors mean well, but they work within a system that is fundamentally designed to create profit for industry, not health for patients. In brief, many people have cured cancer using an incredible variety of methods, including nutritional, dietary, plant, and energy therapies. The reason you do not hear of most of them (in a positive light) is that organizations like the AMA and the ACS exist to disinform the public and protect the medical monopoly on profiting from disease.
Title: Re: Protect and Repair Your Brain
Post by: SelfSovereignty on February 25, 2013, 11:56 pm
... you're a very odd mix of highly educated phrases and bizarrely skewed perspectives, you know that, Tryptamine?  Oh well.  I like you all the same.  Yes, I'm sure you'll be able to sleep much better tonight knowing that   ::)

The origin of a tumor has nothing to do with how I view it.  It is a growth which if untreated will become fatal -- that is indeed part of a person and grown from the very same cells as the rest of their body; you know, the parts that they presumably don't want cut out of them in chunks, as opposed to the tumor which everybody thinks sucks and wants taken out of them.

I'm surprised you have such strong opinions on the subject, given that you're a biologist and it's my understanding that cells mutating during replication is extremely common.  It's part of our day, isn't it?  Usually our immune system kills them before they can multiply and become an issue.  With cancer cells, that doesn't happen, so they keep growing and kill you.  If vitamin C injections work, that's great.  Awesome.  I'll keep it in mind.

But no amount of vitamins or exercise will stave off cancer, old age, and death forever.  Our bodies are not perfect.  They make mistakes.  High doses of good things like ascorbic acid can't make us perfect when we aren't to begin with -- that's why I doubt it.  Not because cancer is an invader that needs to be eradicated.  Because it's our body fucking up to begin with, and a vitamin won't fix that.  Chemotherapy and radiation are extremely unhealthy and ravage the body.  The point is to try and ravage the cancerous growth even more than the rest of you.  Vitamin C does not ravage anything, if it doesn't kill the rest of you, how does it do anything except make the cancer healthier and grow faster?  Obviously this is a gross oversimplification, but you see my logic, I'm sure.

That's why I said what I said, and why I still don't believe it -- and why I won't until I someday have a double-blind study put in front of my face.  Nothing personal... :)
Title: Re: Protect and Repair Your Brain
Post by: KandyKidd on February 26, 2013, 12:51 am
Very interesting, saving for later. I don't wana read rite now lol
Title: Re: Protect and Repair Your Brain
Post by: Tryptamine on February 26, 2013, 01:01 am
... you're a very odd mix of highly educated phrases and bizarrely skewed perspectives, you know that, Tryptamine?  Oh well.  I like you all the same.  Yes, I'm sure you'll be able to sleep much better tonight knowing that   ::)

The origin of a tumor has nothing to do with how I view it.  It is a growth which if untreated will become fatal -- that is indeed part of a person and grown from the very same cells as the rest of their body; you know, the parts that they presumably don't want cut out of them in chunks, as opposed to the tumor which everybody thinks sucks and wants taken out of them.

I'm surprised you have such strong opinions on the subject, given that you're a biologist and it's my understanding that cells mutating during replication is extremely common.  It's part of our day, isn't it?  Usually our immune system kills them before they can multiply and become an issue.  With cancer cells, that doesn't happen, so they keep growing and kill you.  If vitamin C injections work, that's great.  Awesome.  I'll keep it in mind.

But no amount of vitamins or exercise will stave off cancer, old age, and death forever.  Our bodies are not perfect.  They make mistakes.  High doses of good things like ascorbic acid can't make us perfect when we aren't to begin with -- that's why I doubt it.  Not because cancer is an invader that needs to be eradicated.  Because it's our body fucking up to begin with, and a vitamin won't fix that.  Chemotherapy and radiation are extremely unhealthy and ravage the body.  The point is to try and ravage the cancerous growth even more than the rest of you.  Vitamin C does not ravage anything, if it doesn't kill the rest of you, how does it do anything except make the cancer healthier and grow faster?  Obviously this is a gross oversimplification, but you see my logic, I'm sure.

That's why I said what I said, and why I still don't believe it -- and why I won't until I someday have a double-blind study put in front of my face.  Nothing personal... :)
Cancer does not form from an 'original sin' mutation in one cell that divides uncontrollably to create a tumor; it is a tendency of cellsto metabolize in a toxic and inefficient way, that promotes their own survival at the expense of their surroundings. It is caused by the breakdown of the normal factors that normally compel cells to remain differentiated. Literally everything will have some effect on a tumor, whether it promotes or destroys it. The idea that chemotherapy, radiation, and surgery are somehow the only possible cures for cancer is similar to the theory that depression is caused by a deficiency of antidepressants
As for vitamin C, virtually all animals synthesize ascorbate in their livers. Only apes and guinea pigs have lost this ability, and both obtain very high amounts of it from their diets. Modern humans rarely consume even 1% of the ascorbate they would be getting on a plant-based diet, and should be thought of as severely deficient. Ascorbate is a cofactor in many diverse reactions, including, as I mentioned earlier, the hydroxylation of proline in collagen. Its deficiency produces a tendency for cancer to spread, and it inactivates the enzymes that tumors secrete to dissolve extracellular matrix. Ascorbate levels in cancer patients tend to be much lower than normal. Surgery, radiation, and chemotherapy further deplete ascorbate. Historical reports suggest that untreated scurvy was commonly associated with cancer. Sufficient vitamin C can in some cases allow the body to encapsulate a tumor in collagen. It also promotes increased formation of lymphocytes.
Do you have any better reasons why someone with cancer should not take vitamin C?
Title: Re: Protect and Repair Your Brain
Post by: SelfSovereignty on February 26, 2013, 01:06 am
Do you have any better reasons why someone with cancer should not take vitamin C?

Perhaps I misspoke.  I'm not trying to tell you or anyone else that it definitely does not work and shouldn't be bothered with.  I'm trying to say that I do not believe that it works, and will not until I see some objective evidence that it does.  As I said, if it works, then awesome.  I'll remember it for when I get cancer from all the drugs I take, hah.

I didn't mean to say that it HURTS someone, or that you shouldn't do it ever for any reason.  That would be silly.  I'm just saying I have healthy doubts about such a fantastic claim.  Is that not reasonable or something...?
Title: Re: Protect and Repair Your Brain
Post by: Tryptamine on February 26, 2013, 02:50 am
Do you have any better reasons why someone with cancer should not take vitamin C?

Perhaps I misspoke.  I'm not trying to tell you or anyone else that it definitely does not work and shouldn't be bothered with.  I'm trying to say that I do not believe that it works, and will not until I see some objective evidence that it does.  As I said, if it works, then awesome.  I'll remember it for when I get cancer from all the drugs I take, hah.

I didn't mean to say that it HURTS someone, or that you shouldn't do it ever for any reason.  That would be silly.  I'm just saying I have healthy doubts about such a fantastic claim.  Is that not reasonable or something...?

There is an enormous amount of evidence that it works, including countless peer reviewed studies. If you had looked you would have found. People assume there must not be or else it would be widely used, but lack of evidence is not  a reason why vitamin C is not commonly used against cancer by mainstream medicine.
Skepticism is fine. On the other hand, I'd say it's a safe assumption that correcting severe, chronic vitamin deficiencies would improve resistence to cancer.
Title: Re: Protect and Repair Your Brain
Post by: poolsclosed on February 26, 2013, 03:17 am
Trypt, do you follow any particular dietary restrictions, e.g. veganism? I know you make a point to eat plenty of fresh fruits, particularly citrus fruits, but I'd be curious as to what you elect to cut from your diet, besides so-called "processed" foods containing toxic additives and lacking their original nutrients, I'd assume.
Title: Re: Protect and Repair Your Brain
Post by: Tryptamine on February 26, 2013, 06:03 am
I don't eat any meat or dairy and most of what I eat is raw fruit. I've recently stopped eating bread. I avoid all oils except coconut, which I use extensively.
Title: Re: Protect and Repair Your Brain
Post by: poolsclosed on February 27, 2013, 01:30 am
I don't eat any meat or dairy and most of what I eat is raw fruit. I've recently stopped eating bread. I avoid all oils except coconut, which I use extensively.
No meat or dairy, but any eggs? Which foods serve as your primary sources of protein? Also, kudos on the bread.
Title: Re: Protect and Repair Your Brain
Post by: Tryptamine on February 27, 2013, 02:20 am
I don't eat any meat or dairy and most of what I eat is raw fruit. I've recently stopped eating bread. I avoid all oils except coconut, which I use extensively.
No meat or dairy, but any eggs? Which foods serve as your primary sources of protein? Also, kudos on the bread.

Fruit has a decent amount of protein and a-keto acids (which are converted into amino acids) when you divide out its water content. I also sometimes take a bit of Pea/Cranberry/Hemp protein powder. And quinoa.
Title: Re: Protect and Repair Your Brain
Post by: Holly on February 27, 2013, 05:20 am
I don't eat any meat or dairy and most of what I eat is raw fruit. I've recently stopped eating bread. I avoid all oils except coconut, which I use extensively.
No meat or dairy, but any eggs? Which foods serve as your primary sources of protein? Also, kudos on the bread.

Fruit has a decent amount of protein and a-keto acids (which are converted into amino acids) when you divide out its water content. I also sometimes take a bit of Pea/Cranberry/Hemp protein powder. And quinoa.

Can you say your diet has drastically improved the quality of your life?  What does your daily eating habits look like? Very curious.
Title: Re: Protect and Repair Your Brain
Post by: poolsclosed on February 27, 2013, 04:52 pm
Fruit has a decent amount of protein and a-keto acids (which are converted into amino acids) when you divide out its water content. I also sometimes take a bit of Pea/Cranberry/Hemp protein powder. And quinoa.
I beg to differ on the protein content. Just as you see modern diets as deficient in Vitamin C, I see modern diets as deficient in protein, and lacking a variety of amino acids. This is why I ask where you get your protein from. Unless you weigh something like 30kg I can't see you getting enough protein to match your lean body mass, unless you're eating an excessive amount of calories from all the starches in the fruit. I find it strange that you say you only sometimes take hemp protein. Hemp is an excellent vegan protein source, better than soy in my opinion because of the phytoestrogen in soy... so I just wonder how your macronutrient profile must look. I enjoy hearing about this, since I've always taken a low carb approach, but a mostly-fruit diet is anything but.
Title: Re: Protect and Repair Your Brain
Post by: Tryptamine on February 27, 2013, 07:48 pm
Fruit has a decent amount of protein and a-keto acids (which are converted into amino acids) when you divide out its water content. I also sometimes take a bit of Pea/Cranberry/Hemp protein powder. And quinoa.
I beg to differ on the protein content. Just as you see modern diets as deficient in Vitamin C, I see modern diets as deficient in protein, and lacking a variety of amino acids. This is why I ask where you get your protein from. Unless you weigh something like 30kg I can't see you getting enough protein to match your lean body mass, unless you're eating an excessive amount of calories from all the starches in the fruit. I find it strange that you say you only sometimes take hemp protein. Hemp is an excellent vegan protein source, better than soy in my opinion because of the phytoestrogen in soy... so I just wonder how your macronutrient profile must look. I enjoy hearing about this, since I've always taken a low carb approach, but a mostly-fruit diet is anything but.
Modern diets indeed contain an imbalance of amino acids. People consume too much tryptophan and cysteine, glutamate and aspartate, and not enough of other amino acids, from protein in skeletal muscle ("meat"), dairy, and grains. These cause chronic stress and produce a catabolic state, where proteins are constantly being broken down and amino acids are constantly lost. The composition of the protein is perhaps even more important than the total amount consumed.
Dietary amino acids are necessary only insofar as new protein needs to be produced, or catabolized protein needs to be replaced. On a mainly fruit diet, one's 'need' for protein is far decreased. Granted, most fruits today are not as high in protein as wild tropical fruits, which is why I supplement with hemp/pea/cranberry protein - but chimpanzees and bonobos subsist virtually entirely on fruit, and are much more physically fit than the average human. Why don't they need protein powder?
Fruit is typically very low in starch, and high in simple sugars. Sugar is the only fuel your brain imports. It is the ideal energy source. Protein should not be relied upon as energy; it is needed for the construction of new protein, but if your body is oxidizing amino acids for energy you've got a problem (chances are you're starving, out of blood sugar / glycogen /fat / ketones and your muscles are being broken down for energy). Breaking down amino acids produces ammonium and nitric oxide.
A low carb diet is in my view not suited to human physiology. Sugar from fruit is the only fuel capable of supporting the optimal function of an enormous primate brain. Starch is harmful, because it cannot be immediately metabolized/imported into cells, and produces insulin resistence by constantly releasing glucose, which ultimately precludes the use of sugar as an energy source (ie diabetes).
Title: Re: Protect and Repair Your Brain
Post by: poolsclosed on February 27, 2013, 08:55 pm
Fruit has a decent amount of protein and a-keto acids (which are converted into amino acids) when you divide out its water content. I also sometimes take a bit of Pea/Cranberry/Hemp protein powder. And quinoa.
I beg to differ on the protein content. Just as you see modern diets as deficient in Vitamin C, I see modern diets as deficient in protein, and lacking a variety of amino acids. This is why I ask where you get your protein from. Unless you weigh something like 30kg I can't see you getting enough protein to match your lean body mass, unless you're eating an excessive amount of calories from all the starches in the fruit. I find it strange that you say you only sometimes take hemp protein. Hemp is an excellent vegan protein source, better than soy in my opinion because of the phytoestrogen in soy... so I just wonder how your macronutrient profile must look. I enjoy hearing about this, since I've always taken a low carb approach, but a mostly-fruit diet is anything but.
Modern diets indeed contain an imbalance of amino acids. People consume too much tryptophan and cysteine, glutamate and aspartate, and not enough of other amino acids, from protein in skeletal muscle ("meat"), dairy, and grains. These cause chronic stress and produce a catabolic state, where proteins are constantly being broken down and amino acids are constantly lost. The composition of the protein is perhaps even more important than the total amount consumed.
Dietary amino acids are necessary only insofar as new protein needs to be produced, or catabolized protein needs to be replaced. On a mainly fruit diet, one's 'need' for protein is far decreased. Granted, most fruits today are not as high in protein as wild tropical fruits, which is why I supplement with hemp/pea/cranberry protein - but chimpanzees and bonobos subsist virtually entirely on fruit, and are much more physically fit than the average human. Why don't they need protein powder?
Fruit is typically very low in starch, and high in simple sugars. Sugar is the only fuel your brain imports. It is the ideal energy source. Protein should not be relied upon as energy; it is needed for the construction of new protein, but if your body is oxidizing amino acids for energy you've got a problem (chances are you're starving, out of blood sugar / glycogen /fat / ketones and your muscles are being broken down for energy). Breaking down amino acids produces ammonium and nitric oxide.
A low carb diet is in my view not suited to human physiology. Sugar from fruit is the only fuel capable of supporting the optimal function of an enormous primate brain. Starch is harmful, because it cannot be immediately metabolized/imported into cells, and produces insulin resistence by constantly releasing glucose, which ultimately precludes the use of sugar as an energy source (ie diabetes).
Catabolism is to be avoided, this I agree. Using protein for energy is very unhealthy. So I don't eat a diet consisting mainly of protein and lipids. However, the fact that other animals can eat carbohydrate-heavy diets shouldn't influence our diets too much. You say so yourself, we need Vitamin C much more than pretty much every other animal on this planet. It's my opinion that relying on sugar as your main macronutrient has many negative implications on your health, the primary of which would obviously be hypoglycemia from constant sugar spikes and crashes. There's also a very rapid weight gain from excess calories, and the weight's harder to put off than excess protein or fat, if I remember correctly, due to the way the body stores excess carbohydrates over other macronutrients. And it may be total conjecture on my part to say this - however it is still my opinion - that burning fat cells accumulated from carbohydrate consumption poses just as much of a toxic threat as burning dietary amino acids or lipids. So the goal would be to micromanage a mostly-sugar diet, wouldn't it? I assume that's what you have to do - snack all day, which is probably better for you anyway. It's still taxing.

My diet involves avoiding spikes of insulin at any time, so I guess it's a low carb and low GI diet. I aim for around 150g of carbohydrates a day. If I'm training, I sometimes eat up to 150g of protein a day, but as you said the need for amino acids changes then, since the body needs to build new cells. Normally I try to get 50g or more. I don't eat clean, out of frugality. I will probably die young. :( I still find the contrast in our diets interesting. I've managed to stabilize my blood sugars much more through my diet, and my energy levels are very consistent nowadays, so it must be doing some good.
Title: Re: Protect and Repair Your Brain
Post by: gtgeorgz on February 28, 2013, 01:16 am
Interested in purchasing your MindFood caps.. just wondering would this help protect my brain if I take a cap BEFORE taking some MDMA as well? Will it enhance or dull the effects of MDMA?
Anyone got any experience of this?
Cheers.
Title: Re: Protect and Repair Your Brain
Post by: Tryptamine on February 28, 2013, 01:39 am
Fruit has a decent amount of protein and a-keto acids (which are converted into amino acids) when you divide out its water content. I also sometimes take a bit of Pea/Cranberry/Hemp protein powder. And quinoa.
I beg to differ on the protein content. Just as you see modern diets as deficient in Vitamin C, I see modern diets as deficient in protein, and lacking a variety of amino acids. This is why I ask where you get your protein from. Unless you weigh something like 30kg I can't see you getting enough protein to match your lean body mass, unless you're eating an excessive amount of calories from all the starches in the fruit. I find it strange that you say you only sometimes take hemp protein. Hemp is an excellent vegan protein source, better than soy in my opinion because of the phytoestrogen in soy... so I just wonder how your macronutrient profile must look. I enjoy hearing about this, since I've always taken a low carb approach, but a mostly-fruit diet is anything but.
Modern diets indeed contain an imbalance of amino acids. People consume too much tryptophan and cysteine, glutamate and aspartate, and not enough of other amino acids, from protein in skeletal muscle ("meat"), dairy, and grains. These cause chronic stress and produce a catabolic state, where proteins are constantly being broken down and amino acids are constantly lost. The composition of the protein is perhaps even more important than the total amount consumed.
Dietary amino acids are necessary only insofar as new protein needs to be produced, or catabolized protein needs to be replaced. On a mainly fruit diet, one's 'need' for protein is far decreased. Granted, most fruits today are not as high in protein as wild tropical fruits, which is why I supplement with hemp/pea/cranberry protein - but chimpanzees and bonobos subsist virtually entirely on fruit, and are much more physically fit than the average human. Why don't they need protein powder?
Fruit is typically very low in starch, and high in simple sugars. Sugar is the only fuel your brain imports. It is the ideal energy source. Protein should not be relied upon as energy; it is needed for the construction of new protein, but if your body is oxidizing amino acids for energy you've got a problem (chances are you're starving, out of blood sugar / glycogen /fat / ketones and your muscles are being broken down for energy). Breaking down amino acids produces ammonium and nitric oxide.
A low carb diet is in my view not suited to human physiology. Sugar from fruit is the only fuel capable of supporting the optimal function of an enormous primate brain. Starch is harmful, because it cannot be immediately metabolized/imported into cells, and produces insulin resistence by constantly releasing glucose, which ultimately precludes the use of sugar as an energy source (ie diabetes).
Catabolism is to be avoided, this I agree. Using protein for energy is very unhealthy. So I don't eat a diet consisting mainly of protein and lipids. However, the fact that other animals can eat carbohydrate-heavy diets shouldn't influence our diets too much. You say so yourself, we need Vitamin C much more than pretty much every other animal on this planet. It's my opinion that relying on sugar as your main macronutrient has many negative implications on your health, the primary of which would obviously be hypoglycemia from constant sugar spikes and crashes. There's also a very rapid weight gain from excess calories, and the weight's harder to put off than excess protein or fat, if I remember correctly, due to the way the body stores excess carbohydrates over other macronutrients. And it may be total conjecture on my part to say this - however it is still my opinion - that burning fat cells accumulated from carbohydrate consumption poses just as much of a toxic threat as burning dietary amino acids or lipids. So the goal would be to micromanage a mostly-sugar diet, wouldn't it? I assume that's what you have to do - snack all day, which is probably better for you anyway. It's still taxing.

The only other animals that cannot produce vitamin C are fruit-eating primates, and guinea pigs. Fruit is the best source of vitamin C, as well as countless other beneficial substances that have co-evolved with primates for tens of millions of years.
Have you ever seen someone on an all-fruit diet who was fat? Sugar does not become fat unless it remains unused. Long chain unsaturated fats like fish and seed oils lower the metabolic rate by inhibiting thyroid function, while saturated fats in some fruits stimulate it.


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My diet involves avoiding spikes of insulin at any time, so I guess it's a low carb and low GI diet. I aim for around 150g of carbohydrates a day. If I'm training, I sometimes eat up to 150g of protein a day, but as you said the need for amino acids changes then, since the body needs to build new cells. Normally I try to get 50g or more. I don't eat clean, out of frugality. I will probably die young. :( I still find the contrast in our diets interesting. I've managed to stabilize my blood sugars much more through my diet, and my energy levels are very consistent nowadays, so it must be doing some good.

Try adding fruit smoothies to your diet, see how that makes you feel. Use coconut or hemp milk instead of dairy, and it's best if you make the nut milk yourself (it's easy, look it up). Many people have an irrational fear of sugar, when it fact it comprises the entire fuel source of your brain. If you do not eat sugar, your body will convert whatever you do eat (including protein) into sugar, to fuel your brain (and other organs). You're not doing yourself any good by avoiding it.
Title: Re: Protect and Repair Your Brain
Post by: Tryptamine on February 28, 2013, 01:51 am
Interested in purchasing your MindFood caps.. just wondering would this help protect my brain if I take a cap BEFORE taking some MDMA as well? Will it enhance or dull the effects of MDMA?
Anyone got any experience of this?
Cheers.

Taking a capsule a couple hours before taking MDMA will generally enhance its beneficial effects while preventing the associated discomfort and subsequent lethargy.
Title: Re: Protect and Repair Your Brain
Post by: poolsclosed on February 28, 2013, 03:10 am
The only other animals that cannot produce vitamin C are fruit-eating primates, and guinea pigs. Fruit is the best source of vitamin C, as well as countless other beneficial substances that have co-evolved with primates for tens of millions of years.
Have you ever seen someone on an all-fruit diet who was fat? Sugar does not become fat unless it remains unused. Long chain unsaturated fats like fish and seed oils lower the metabolic rate by inhibiting thyroid function, while saturated fats in some fruits stimulate it.

Try adding fruit smoothies to your diet, see how that makes you feel. Use coconut or hemp milk instead of dairy, and it's best if you make the nut milk yourself (it's easy, look it up). Many people have an irrational fear of sugar, when it fact it comprises the entire fuel source of your brain. If you do not eat sugar, your body will convert whatever you do eat (including protein) into sugar, to fuel your brain (and other organs). You're not doing yourself any good by avoiding it.
I've never seen anyone eat an all-fruit diet! Although wellness goes beyond a healthy body fat % so of course while I make references to weight gain as being unhealthy I try to keep it all in perspective of healthy body fat % and how it accumulates and dissipates and so on. I do note what you say about the saturated fats, though... I wanna keep my thyroid working well.

As for the smoothies, I'll skip the process and just eat the fruits directly. I realize that glucose is what fuels the brain, so I keep my blood glucose levels stable by not avoiding carbohydrates but not relying on them either. So I get what you're saying and I hope you realize that I don't avoid them, I just never eat large amounts at once and I try to get my carbohydrates from produce, not grain or processed sugars.

Thanks for all the advice. Really, thank you, it's highly appreciated. :)
Title: Re: Protect and Repair Your Brain
Post by: gtgeorgz on February 28, 2013, 11:55 am
Okay cool, will probably place an order today then.
What is the shelf life of this product?
Also would there be any issues taking this product along side Piracetam?
Title: Re: Protect and Repair Your Brain
Post by: Tryptamine on February 28, 2013, 06:49 pm
Hard to say, but this new formulation should stay fresh for months. Best if stored in a cool, dry, dark place.
There are no issues taking MindFood with piracetam, I do so frequently.
Title: Re: Protect and Repair Your Brain
Post by: nitpi950 on February 28, 2013, 06:51 pm
Hard to say, but this new formulation should stay fresh for months. Best if stored in a cool, dry, dark place.
There are no issues taking MindFood with piracetam, I do so frequently.
Bet you wish your parents had named you "nootropic" instead eh
Title: Re: Protect and Repair Your Brain
Post by: Tryptamine on March 01, 2013, 04:40 pm
Hard to say, but this new formulation should stay fresh for months. Best if stored in a cool, dry, dark place.
There are no issues taking MindFood with piracetam, I do so frequently.
Bet you wish your parents had named you "nootropic" instead eh

They did.
Title: Re: Protect and Repair Your Brain
Post by: atlas on March 02, 2013, 01:24 pm
There are no issues taking MindFood with piracetam, I do so frequently.

Just bought some of your mindfood and placed an order for piracetam.

I need to study intensively for a couple months
What is a recommended dosage to start with?
Any other tips? (this could help others too :) )

We're very glad to have someone like you in our community
Cheers tryp :)
Title: Re: Protect and Repair Your Brain
Post by: Tryptamine on March 02, 2013, 06:40 pm
Start with one capsule.
Most important for optimal brain health is to eat as much fruit as possible, avoiding grains, liquid oils, and muscle meat.
Title: Re: Protect and Repair Your Brain
Post by: Tryptamine on March 29, 2013, 08:43 am
Due to price increases, non-US orders now have a $150 minimum. I will continue to give free advice to anyone who asks for it.
Title: Re: Protect against brain damage, improve your cognition & fall asleep naturally.
Post by: Cosette on May 03, 2013, 01:26 am
5-HTP is excitatory, anti-metabolic, stress-promoting (growth-hormone, prolactin, and cortisol-releasing) pro-inflammatory, potentially carcinogenic monoamine. It is released from platelets and mast cells in response to injury or stress, promoting the constriction of blood vessels and formation of clots. In light of this, most substances that produce a stress response are 'serotonin reuptake inhibitors' which decrease its intracellular concentration and cause it to be released. Its energy-suppressing properties are associated with a variety of chronic energy-related diseases, as well as hibernation.

One of the primary ways by which drugs like psilocin and LSD can so profoundly expand our consciousness is by antagonizing or decreasing the activity of serotonin, which itself has the opposite properties than those that are typically ascribed to it. Psychedelic drugs do not work merely by increasing the activity of sn effect which can potentially be propagated indefinitely. Serotonin is 'released' because its place has been taken by MDMA, and when erotonin; generally speaking, they replace it in binding sites on proteins, and exert slightly different electronic effects on the protein, which alters its electronic environment, ait diffuses out of the cell it is prone to being metabolized. It may interact with nearby cells, but the characteristic effects of psychedelics  are due to their specific electronic effects, not just the endogenous monoamines which they displace. Serotonin's subjective effects include tropor, helplessness, tranquilization, migraine, and apathy. SSRIs drastically increase the risk of suicide in people who take them, probably for this reason.

Most people's diets contain high levels of tryptophan as well, from muscle meat, fish, dairy, soy, and some vegetables. During infancy and childhood it promotes growth, but during adulthood it is potentially carcinogenic and inhibits differentiation. So supplementing with 5-HTP in the vast majority of cases is harmful in the long term, although the acute effects can vary widely depending on how it's utilized and how your body compensates for its consumption ...

Many herbs and vitamins are themselves COX inhibitors (for example: Vitamin C, Oligomeric Proanthocyanidins, Alpha Lipoic Acid, Sulbutiamine (if thiamine is deficient), TMG, Pyridoxal (B6),  Naicin (B3), Ginkgo, Rhodiola, Bacopa, Holy Basil, and countless others). MindFood contains all of these; ThinkDeep and ChillPill contain many of them. I would not recommend taking a pharmaceutical drug specifically to inhibit COX; no metabolic process exists in a vacuum, and targeting that specific enzyme with a potent, specific drug will invariably cause imbalances elsewhere. If you really want to go that route, perhaps you could try white willow bark extract, which was the natural inspiration for the less effective and more toxic drug Aspirin ...

Bottom line: stop taking pro-oxidant, anti-metabolic substances (iron, PUFA oils (fish, flax, soy, sunflower), 5-HTP/serotonin, amphetamines, glutamate/aspartate), start taking anti-oxidant, pro-metabolic substances (the ones I listed earlier, as well as coconut oil to replace the aforementioned polyunsaturated fat oils), and you can generally prevent neurotoxicity without pushing your metabolism unsustainably in one direction. Metabolism is far more interconnected and fundamental than the membrane/receptor/pump/channel/transporter model implies.

This quote is an oldie but a good one. Quoted to keep handy :). +1 from me.
Title: Re: Protect and Repair Your Brain
Post by: poolsclosed on May 14, 2013, 04:34 am
Trypt, just wanna say after your advice I have mostly eliminated dairy milk from my diet in favor of hemp milk and have moved most of my carbohydrate intake to fresh fruit. My energy levels are generally better, although I have to eat consistently over the day to avoid hypoglycemia, which is a tradeoff I'm willing to make since I do feel a lot healthier. Thanks for the advice. BTW, hemp protein is really gross...  ::)
Title: Re: Protect and Repair Your Brain
Post by: Tryptamine on May 16, 2013, 12:12 am
Trypt, just wanna say after your advice I have mostly eliminated dairy milk from my diet in favor of hemp milk and have moved most of my carbohydrate intake to fresh fruit. My energy levels are generally better, although I have to eat consistently over the day to avoid hypoglycemia, which is a tradeoff I'm willing to make since I do feel a lot healthier. Thanks for the advice. BTW, hemp protein is really gross...  ::)

Good to hear. You can make your own milks by grinding up dried coconut/almond/hempseed, blending with warm water, and filtering through a cheesecloth or nut-milk bag.
For protein I use sunwarrior, hemp/cranberry/pea protein, it doesn't taste bad.
Title: Re: ⋋ Better Living Through Neurochemistry 乂 Protect, Repair & Enhance Your Brain ⋌
Post by: Tryptamine on July 24, 2013, 05:43 pm
Re-listed MindFood and ChillPill, although it'll probably be a couple of days before I fill new orders.

http://silkroadvb5piz3r.onion/silkroad/item/34c8f590d2
http://silkroadvb5piz3r.onion/silkroad/item/4dc5679867
Title: Re: ⋋ Better Living Through Neurochemistry 乂 Protect, Repair & Enhance Your Brain ⋌
Post by: b999 on July 25, 2013, 12:42 pm
Would your stuff be legal to send to Australia through customs?  Got any scientific evidence or real life testimonies of your stuff actually working?  I enjoy meth as a 'nootropic' so I'm keen on ways to minimise harm from meth or even other ways to boost my IQ and metabolism / health and most of the 'commercial' and 'legal' stuff on the market is pretty weak if useful at all (rarely).
Title: Re: ⋋ Better Living Through Neurochemistry 乂 Protect, Repair & Enhance Your Brain ⋌
Post by: Tryptamine on July 26, 2013, 01:40 am
I've sent many orders to Australia. Rolling Stone Magazine Australia interviewed me last year, and wrote that my MindFood was an excellent hangover cure. I've not done randomized double-blind placebo controlled studies, but I have dozens of reviews from SR users, including many well-known vendors, on my review thread, the link to which is in my forum signature.
My supplements are not replacements for stimulants, but they will prevent some of their adverse effects by enhancing your brain's ability to produce energy and withstand stress.