You don't want to snort it or smoke it. It will feel different and not last as long. The bioavailability is nothing but how much of the compound gets into your blood stream. Only IV has 100% bioavailability. 60% means that 60% of what you ingest orally ends up in your blood.The only reason to worry about this *at all* is if you can't afford your oral dose and you want to get that much in your blood more cheaply. Other than that, just ignore it. Oral is the least hazardous in many ways.