Some estimates put the LD50 for meth at 50mg/kg. For an average 60kg person, that's 3 grams it would take to kill half of the people who took it. Half of the ones who had no tolerance, mind you. (Meth)amphetamine is much harder to OD on than cocaine, so whether it's meth or methiopropamine... you're probably going to be surviving either way. Not entirely sure what you're getting at here.