Quote from: bynter on January 12, 2013, 12:27 pmWell right now I have a few concerns, mainly about the physical dangers of meth usage. 1: Recently, my friend(who has ADHD[which I believe is due to low dopamine levels] but also has a family history of schizophrenia[which I'm pretty is caused by high dopamine levels] took about 15mg of Lorazepam, and 140mg of Vyvanse, which led to him going into psychosis for nearly 16 hours. What should I make out of this? Your friend should never take amphetamines ever, ever again. 140mg putting someone in a truly psychotic state for 16 hours is not good. I mean it's beyond not good, they're either hypersensitive due to an allergy of some kind or they're so close to psychotic to begin with that their brain cannot tolerate amphetamine use. If they continue to use amphetamines, it's going to be bad. They may develop schizophrenia anyway, but it will be worse and sooner if they take amphetamines I'm willing to bet.