You're not the only one. It's a constant issue for me, actually. I do my best to keep the tylenol, aspirin, and advil to an absolute minimum (as if I'm not already doing enough damage to my liver and kidneys), but basically: it's part of tweaking for 3 days straight.The cellular trauma that your body sustains by simply being alive and active is repaired during sleep cycles (maybe only REM, but frankly I don't know). Skip that for a couple of days, so that it keeps adding up. Then pile on the extra damage from being active when you should have been sleeping. Then pile on the tenseness you get from powerful stimulants. And try to avoid piling on compulsiveness making you do stupid shit like fuck with skin imperfections or something (seriously, you really cannot tweak regularly and let yourself do that, you will fuck your appearance up badly).Just part of the drug, unfortunately.