Silk Road forums
Market => Product requests => Topic started by: teamwhitehawk on March 05, 2012, 10:26 pm
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I am a skilled organic chemist in need of basic organic Laboratory equipment This means: vaccuum filtration devices, distilation apparatuses, reflux boilers, column chromatographs, CHEAP NMR AND IR spectrophotometers, evaporators, round bottom flasks, buchner funnels, test tubes, solvents, hoods, melttemp machines,....etc etc.. you get the point.....) I dont care if this equipment is used, stolen, written off, WHATEVER!!! I DONT CARE WHERE IT COMES FROM AS LONG AS IT DOESNT COME WITH GPS TRACKING OR ANYTHING TO TRACE IT ...... I WILL BUY THESE THINGS FROM YOU STRAIGHT UP ....
IF I can also get a connect on black list chemicals for LSD .... this includes certain solvents, LSA from ergotamine and its salts, diethyl amide, and specific solvents and gases ...... IF you can get it then i need to continue no further..... please contact me .....
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Lol, if you're a skilled organic chemist you sure do have some amusing names for common lab equipment. Do you really reckon you could run an NMR machine by yourself? Where are you gonna get the liquid helium and weekly refills or liquid nitrogen to run it?
And you reckon you use diethyl amide to make acid? ;D
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Nitrogen tanks are not an issue ... easily acquired from my university ..... Use (dimethylamine) (sorry sp) in a solution of dimethylformamide.... and ive never known liquid helium to run the nmr ... its ok im still learning .... and what amusing names ? i didnt ask for flak ... just assistance.....
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i should say that nomenclature also is not my strong forte' .... However i understand chemical mechanisms extremely well
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I recommend reading Strike's groundbreaking work: 'Sources' before you do anything. He has a lot of intelligent advice on this niche subject.
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Don't come in saying you're a skilled chemist if you're not, I know it's tempting when you're an undergrad and learn a few funky looking mechanisms but it's a long climb to being even passably competent.
Come here looking for help and advice and you'll get heaps, there are a few active chemists on here.
You need huge volumes of Liquid Nitrogen to run an NMR machine, why do you think that boc lorry delivers to the back of your uni department 3 times a week? If you've learnt any NMR stuff yet, you'll know that the coil needs to be kept at about 4K to be superconductive- this is achieved by it sitting in liquid helium. Liquid helium is fucking expensive so to keep it from boiling off too quickly, a secondary reservoir of cheaper liquid nitrogen is used.
And if you don't maintain this, you will get magnet quench- youtube this to see why it might not be such a good idea.
And you don't use dimethylamine for LSD, you use diethylamine. You probably wouldn't use it in a DMF solution either, most of the modern methods of amide bond formation (pyBOP, TFFH etc) just would use dry DCM.
Nomenclature is soo important, it's easy to get well grounded in it- the IUPAC gold book is your friend.
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@wowzers
Is it correct to say that although LSD is the most finicky drug for a chemist to synthesize, it is also the most lucrative if you have the ability to move the product?
I think I remember reading that 1 pound of pure LSD is worth an absolutely staggering amount of money. So here is a back of the envelope calculation based on street level prices and you can tell me whether I'm correct or not:
250 micrograms is a hit, that costs ~$15 dollars, 1 milligram is $60 dollars, which makes a gram worth $60000 dollars, which makes 1 pound worth $27,180,000 dollars. Obviously bulk prices are much lower, but a fraction of 27 million dollars is still a whole lot of moolah.
Best the hell out of cocaine and meth, ha!
But seriously, this prompts the question: just how difficult (time and money, equipment and knowledge) is it to create 1 pound of LSD?
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Sorry wowzers, again me trying to answer... ;)
Cost is in ergot for synthesis. That is hard to get, it can be grown and extracted what need a time and the place. Synthesis itself is not so complicated and solvents are cost effective.
Manufacturer is rare in whole process - from production to retail sale. But regardless, profit is very high.
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Yeah it is hugely profitable, I've heard out-the-lab prices of $10k/g but obviously the LSD world is super secretive.
If you can get hold of reasonably pure ergotamine tartrate, making LSD is pretty damn easy for a chemist with a bit of grad school behind them. I'm by no means a talented chemist but I've worked successfully on the total synthesis of a series of natural products which are an order of magnitude more unstable and complex than lysergic acid.
Once you've isolated lysergic acid, there's a hundred ways of making an amide from that carboxylic acid and there's a load of reagents which have been specifically designed to use on sensitive substrates.
As with any chemistry, the difficult bit is scale up. Chemistry which works on 50mg won't necessarily work on 100g. However, as peptide coupling is performed on multi-kilo scales in pharma, there's bound to be a protocol suitable for 100g batches of LSD.
** mseller succinctly summarises the above nonsense 10 minutes ahead of me again ;)
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Haha this thread just gave me a good laugh. By hood I assume you mean fume hood ... i'll get right on stealth shipping that to you along with the very expensive NMR instrument and massive quantities of nitrogen you'd need to run it as discussed already !
Wowzers you're a big asset to this community :)
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This guy definitely sounds like he just finished ochem2. If you go looking for all that shit at one time from one source, even on SR, your gonna draw some attention from somewhere, esp IR and NMR, even if you are a research assistant or whatever you do at your school. Half that shit you don't have to get thru SR, like tubes, and the distilation ap, and most glass can be peiced out on ebay. Good luck with lsd, those rxns can be very dangerous, not to mention fucking unforgiving as fuck.