Prices will ultimately decline, partly for the reason you suggest: lower risk of interception.Profits will increase, due to an uptick in trade e.g. people who wouldn't normally take drugs such as MDMA or amphetamine will now do so, as well as the decline in prices encouraging traditional drug consumers.However due to increasing purity and availability, while drug consumption will increase overall, I think the increase in knowledge about appropriate dosages, correct practices and increased social acceptance (less "I take drugs to be a rebel y'all") shall reduce the harm, which puts downward pressure on any uptick in those who become chemically dependent. People will find other things to addict themselves to, fully immersed augmented or virtual reality experiences or something.I think the biggest impact is actually none of those things which are so frequently discussed such as the above. The biggest impact shall be entirely new business models and arbitrage strategies. That sounds like 'b-school' nonsense talk, but it actually isn't, search for my posts on "integration" to see why. Today's drug markets are horribly inefficient, and economies of scale creating million percent profits are possible. You read the previous sentence correctly.This is the start of the black market's industrial revolution, SR is the incubator of a gold rush that is going to last a long, long time. This is the time to work hard, build your syndicates, corporations and ancillary technology services and products for those companies, because it'll pay off big time with serious capital, power and money. Today's SRians and Darknet participants are going to be tomorrow's Rockefellers and Vanderbilts. Outside of scale oil/gas and a few other blips, this is the only growth market in America. People who go the traditional route like their parents did are consigned to becoming armies of drones, because in today's world it is unfortunately the case that hard work in the regular market doesn't pay off anymore thanks to a combination of high taxation, high unemployment and low economic prospects. For those with a combination of brains and guts, the Darknet is like virgin uncontested territory, just like the New World used to be. A few pesky Indians/DEA agents to provide high drama and entertainment value, but other than that it's onwards and upwards. Ultimately, as with Tryptamine's vision of the future I hope to see market forces encouraging new drug markets in areas that don't really exist in the mainstream yet, such as nootropic markets (drugs that enhance your mental faculties for specific kinds of work without neurotoxic damage) e.g. you need 10 minutes of pattern recognition ability followed by 20 minutes of creative problem solving. Think dermal patches injecting dozens of different types of drugs via thousands of microinjections depending on your commands as a situation evolves. Certainly it would be a must for academics, soldiers, and many others. We are seeing the start of this on the ground in Iraq and Afghanistan among coalition forces. Future armies are scaling downwards as the cost of equipping and training soldiers accelerates, which means you'll need to get as much bang for your buck as possible, hence chemical enhancement, that is why those soldiers are taking nootropics like moda. Analogous phenomenons exist in the business and academic worlds. It is bizarre that many humans simultaneously think the use of medical drugs outweighs the negative consequences while thinking all other drugs outside of that have equally positive and negative effects, or just negative effects. I'm making it sound a bit like a runaway positive feedback loop, but actually I think it'll occur quite naturally and that existing fears over 'excessive competition' are overblown.tldr; Libertarianism leads to Limitless... :D