Silk Road forums
Market => Product offers => Topic started by: googleyed1 on March 25, 2012, 11:41 pm
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Please leave your interest in this chemical, so we can see if we should bring it to you :)
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Just so you know, Noroxymorphone is a metabolite of oxycodone. Its mainly used for intrathecal use... here is a report about it:
noroxymorphone is a potent μ-opioid receptor agonist when administered intrathecally. The lack of systemic efficacy may indicate reduced ability of noroxymorphone to penetrate the blood–brain barrier due to its low calculated logD value (log octanol/water partition coefficient). Thus, noroxymorphone should have a negligible role in analgesia after systemic administration of oxycodone. Because of its spinal efficacy and long duration of effect, noroxymorphone is an interesting opioid for spinal analgesia with a low potential for abuse. Its safety for spinal administration should be assessed before clinical use.
So, what they are saying is that its a great med for intrathecal (in the spinal area) but it has issues crossing the blood brain barrier when taken via mouth and other routes, except intrathecal...
It looks like this would be an interesting drug to look at. But, it looks like it may work well via iv but not orally. But who knows, Maybe you should get some and get some volunteers to see how well it works, etc. I would love to here reports about it..Im not a shooter, but im sure you could get some volunteers to see how well it works.. its not hard to find out what the dose should be..
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thanks! i had come across that report also, any additional info would be great