This is very interesting, good work!! I think what you will find, especially in the case of cocaine is that active cuts even at lower percentages completely change the feeling, for better or worse. The purest cocaine is much different feeling than street cocaine, its very chill and social like coke was meant to be, but some people prefer the speedy clampjaw feeling of cocaine with active cuts. You may find that some people prefer cocaine with small amounts of active cuts, there is complex pharmacological symbiosis if active cuts are used "correctly".