I have taken opanas before the dawn of time. If you are an I'ver then thats the best option. Still, be careful. If you snort. you can scrape the small coating off or do what i do and just scrape everything together.My dosage nasally is about 20mg, so, I will take 1/2 a 40 and cut that up into about 6 or 7 small lines. After each line, I wait about 3-5 minutes. Rotating nostrils. this gives the med eough time to be absorbed. Plus, it wont goop up in your nose and it will be a much more pleasant experience. The best way to I'v is to do the water extractions (put the pill in water for 24 hours and then filter) the iso route is much quicker and you don't lose too much. so,if you are impatient, that's the best way, but if you can wait 24 hours, do so... Also, if you snort, eat a high fat meal with it. You will find that your experience will go up by at least 10-30 percent. probably around the 15 percent mark, but you will def. feel the difference... Always be careful with opana and and never mix alcohol with it. I know one person who took 4 shots of very high proof alcohol with their opana orally and they damned near died. BE CAREFUL WITH OPANA!!!!