Methadone is a weird animal. it has a very long half life. but a fairly short analgesic half life. Meaning that 10mg will take away the pain for 4 hours or so but the other effects, like the effects on breathing is much longer. this is why many people od on methadone. they take their daily dose and 6 hours later they are again in pain so they take more. The Germans came up with methadone during WWII when they had a shortage of morphine, they came up with methadone. Its a great pain killer and very euphoric. When you take it every day and take 50-100mg of of it daily, your receptors are pretty much slammed. You either have to break through the methadone (which is VERY dangerous) or lower your tolerance. I have found if you lower your tolerance to about 40mg or lower on a daily basis, it doesn't take much to break through it. but dont try if you are not experienced.. But to think of methadone as just a opiate blocker is incorrect. It has a lot of great recreational value. but you must be VERY careful with it. The greatest thing about methadone is that I can go about 2-3 days inbeeween opiate doses before WD will set in. So if you are physically addicted to opiates, I would get some of mselllers stuff and and mix about 30mg of into juice and drink it. Wait a couple hours and if you are still in wd, take another 10mg, but I wouldnt take more than 60mg unless you have one hell of a monster H tolerance.. Methadone is not your average opiate... its something that if your not familiar with that you need to do some studying and figure out what is right for you...