You hit the nail on the head. Snorting it is equal to about 100mg of oxy, but with i.v. you have to be really careful. Well, you need to be careful when you are playing with any size of opana but remember they planned on that 40mg's to be taken by mouth. If you were to get a shot of oxymorphone in the hospital, they would probably not give more than 1-2mg. I've seen just 10mg knock out a very opioid tolerant person. Almost everyone that I have known that first takes a 40 underestimates its strength. They assume that its the same as a 80mg oxy.. Its not. Its much stronger. Always be careful.