Technically, an 80mg oxycontin is equal to 40mg of opana ER. TAKEN ORALLY!! Now, if you snort them, 40mg of opana is 2 or 3 times the strength vs a snorted 80mg oxy. IV its about 3-4 times the strength. Would you consider getting an oxycontin 80mg for 15 or 20 bucks? thats basically what you are paying if you buy an opana 40mg ER for around 60 bucks. If oxycontin users really understood the potency of oxymorphone, the users would be flocking to opana. I have heard that some people will pay 100 bucks for an old school 80mg oc (a year ago, that is) you really have to be careful when you take oxymorphone. Its very potent. Honestly, I know since most people would only pay at the most, 80 bucks for an oc 80 they got it in their heads that they wont pay more than 1 dollar a milligram. But that logic totally goes out the window when your talking 40mgs of opana. I know people that just snort a little and they puke their guts out because of the strength. The only bad thing about opana is that after a 2 or 3 day binge, it will skyrocket your tolerance. Much more so than other narcotics. But, if you do it here and there, your tolerance should be ok. Honestly, opana's really are the best pharmaceutical out there, by far (opiates, that is). Just don't mix it with alcohol and check out opiophile.org and see what they say about opana (oxymorphone)...