I have had multiple customers tell me that they have gotten sick when they have only taken a tiny portion of the Opana. When I mean sick, I mean they get nauseated because they have taken too much. I just wanted to remind everyone that Opana is not oxycontin, It's much much stronger. When someone snorts 30mg of oxycodone, they are really only getting about 50 percent into their system. (thats why eating oxy really is the best way to take it, you get about 80 percent. Shooting you obv. get 100 percent.) I think too many people think that a 40mg opana snorted is equal to 80mg of snorted oc. That is incorrect. Everyone is different. But, snorting 40mg of opana is like snorting around 160-240mg of oxy, maybe higher. Shooting it is even much higher..(no pun intended) Orally, 40mg of opana is equal to 80mg of oxy. Its when you snort and inject that the ratio is much different. I have even gotten nauseated taking it (at first). Always start very small and wait then add if necessary if you are opiate naive.When taken properly, its probably the best opioid out there.. Don't hesitate to ask me any questions. I know some will disagree, but I think the above is a good estimate.. Please be careful.