Ralf Heim is becoming the heir apparent in the line of succession of psychedelic chemistry gods. Shulgin, Nichols, now Heim. Sure there were others, like William Leonard Pickard and Nick Sand, who innovated on production methods, but these guys created whole new classes of drugs. This is one reason why the War on Drugs can't be won. We haven't sampled a fraction of the space of possible organic molecules.