How would you do that, at a mom and pop mailbox company? USPS PO boxes don't have normal street addresses and you can't "set that up" for them. A small, independently owned mailbox company (not a chain like Mailboxes Etc or UPS) is a good option because a lot of times they don't ask for ID and your address is the address of the business. However, I think that simply getting a PO box can be suspicious. It depends on who you are. If you are 40 years old, you may need a PO box for a legitimate business. But how many 20 year olds need PO boxes? Add the fact that this person only gets packages once every few weeks, and never gets regular mail, and it should look suspicious to anyone who bothers to notice. I'm pretty sure that USPS and LE are aware that PO boxes are a popular choice for young people to receive drugs. You might expect this mail to be under higher scrutiny, while mail sent to a private residence is mixed with all the other regular mail. I don't know if any of that is true, but it's something to think about. One thing is certain, PO boxes don't provide additional security, except in cases where you can determine that the package has been compromised before you pick it up, which is rare. Otherwise, renting a PO box can actually make things worse, because you have to take a positive action to pick up the package, whereas you are more of a passive recipient (with higher plausible deniability) of mail that gets stuffed in your home mail box.